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factory supply GMP,DMF Hesperidin
factory supply GMP,DMF Hesperidin
factory supply GMP,DMF Hesperidin
factory supply GMP,DMF Hesperidin
factory supply GMP,DMF Hesperidin

factory supply GMP,DMF Hesperidin

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: USP/EP/BP
  • Payment Terms : L/C,T/T,Other

Keywords

Hesperidin diosmin 520-26-3

Quick Details

  • Appearance:White crystallization
  • Application:Cardiovascular APIs,Sartan antihypertensive drugs
  • PackAge:25kg/drum
  • ProductionCapacity:10|Metric Ton|Day
  • Storage:room temperature
  • Transportation:AIR SEA TRAIN

Details:

Hesperidin Chemical Properties
Melting point  250-255 °C (dec.)(lit.)
alpha  -76 º (c=2,pyridine)
Boiling point  576.16°C (rough estimate)
density  1.3290 (rough estimate)
refractive index  1.5940 (estimate)
storage temp.  Sealed in dry,2-8°C
pka 7.15±0.40(Predicted)
form  Powder
color  light brown
Water Solubility  Insoluble in water. Soluble in organic solvents such as DMSO.
Sensitive  Hygroscopic
Merck  14,4671
BRN  75140
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey QUQPHWDTPGMPEX-QJBIFVCTSA-N
CAS DataBase Reference 520-26-3(CAS DataBase Reference)
EPA Substance Registry System Hesperidin (520-26-3)
History Hesperidin is the glycoside in the form of hesperidin and rubiose and is a derivative of dihydroflavonoids. It widely exists in legume, birch, lip flower, butterfly flower, Rutaceae, and citrus plants. Hesperidin is an important composition of citrus pulp and peel; most of hesperidin exists in citrus processing waste such as skin and fruit bag. Mature skin and tissue have the highest content of hesperidin (30–50% in endocarp; 30–50% in orange collaterals, nuclear, and pulp; and 10–20% in exo_x005fcarp); the content of hesperidin is relatively low in juice and orange bag, which is about 1–5%. The crude extracts of hesperidin was first discovered in 1827 by Lebreton. Then the Hungarian scholar Albert Szent-Gyorgi discovered that the flavonoids have a protective microvascular effect in 1936, which is similar to that of vitamin P. Preparation of vitamin P was made in 1938. It was not until 1949 that it was discovered that vitamin P was made up of two flavonoids, luteolin and hesperidin, which are believed to be vitamin active. This substance, which was later named as vitamin P, was designed to reduce blood vessel permeability and brittleness, as well as alleviate bad blood and vitamin C deficiency. It was later discovered that the substance had an antioxidant effect, so the name of vitamin P was abandoned. Due to the widespread distribution of hesperidin in plant medicine, the research and development have been widely followed.
Uses vitamin P is considered a vascular protector and an anti-inflammatory agent, vitamin P is said to promote capillary health and increase resistance to collagen destruction. Vitamin P is a bioflavonoid that can work in conjunction with vitamin C, helping prevent oxidation of the latter. Vitamin P is found in such food sources as apricots, broccoli, citrus fruit pulp, grapes, prunes, and spinach.
Uses Hesperidin is a flavoring agent that is a bioflavonoid found in citrus pulp. it has minor use as a flavorant.
Uses A flavanone found in citrus fruits, also regarded as Vitamin P.
Uses antiinflammatory, capillary protectant, hypolipidemic
Uses Anticancer

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