CasNo.124750-99-8,factory supply GMP,DMF,CEP Chloramphenicol,(124750-99-8) Suppliers

1 Kilogram	Negotiable

Min.Order :1 Kilogram
Purity: USP/EP/BP
Payment Terms : L/C,T/T,Other

Keywords

Chloramphenicol Losartan 124750-99-8

Quick Details

Appearance:White crystallization
Application:antibiotic;
PackAge:25kg/drum
ProductionCapacity:10|Metric Ton|Day
Storage:room temperature
Transportation:AIR SEA TRAIN

Superiority:

We are very compeitive on Chloramphenicol.Our mfr is GMP certified for this item with CEP document.

Product Name:	Chloramphenicol
CAS:	56-75-7
MF:	C11H12Cl2N2O5
MW:	323.13
EINECS:	200-287-4
Product Categories:	Pyridines;Active Pharmaceutical Ingredients;Antibiotics for Research and Experimental Use;Biochemistry;Others (Antibiotics for Research and Experimental Use);Antibiotic Explorer;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;API;CHLOROMYCETIN;antibiotic;Pharmaceutical intermediates;Chiral Reagents;Pharmaceutical intermediate

Details:

Chloramphenicol Chemical Properties

Melting point	148-150 °C(lit.)
alpha	19.5 º (c=6, EtOH)
Boiling point	644.9±55.0 °C(Predicted)
density	1.6682 (rough estimate)
refractive index	20 ° (C=5, EtOH)
Fp	14 °C
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	absolute ethanol: soluble5-20mg/mL (as a stock solution)
pka	11.03±0.46(Predicted)
form	powder
color	white
Water Solubility	2.5 g/L (25 º C)
Merck	14,2077
BRN	2225532
InChIKey	WIIZWVCIJKGZOK-RKDXNWHRSA-N
CAS DataBase Reference	56-75-7(CAS DataBase Reference)
NIST Chemistry Reference	Chloramphenicol(56-75-7)
IARC	2A (Vol. Sup 7, 50) 1990
EPA Substance Registry System	Chloramphenicol (56-75-7)

Chloramphenicol Usage And Synthesis

Description

Chloramphenicol, also known as chlornitromycin, is a broad-spectrum, bacteriostatic antibiotic derived from Streptomyces venezuelae. It is first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. The synthetic product is racemic, also called synthomycin. Syntomycin is a mixture of chloramphenicol L-isomer and d-isomer. Because of dextroisomer antibacterial effect, the effect of synthomycin is only half of the natural products. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It is effective against several gram-positive and gram-negative bacteria and commonly used in researching protein synthesis and to select for chloramphenicol-resistant transformed cells or the bacterial CAT gene.
Chloramphenicol is a semisynthetic, broad-spectrum antibiotic derived from Streptomyces venequelae with primarily bacteriostatic activity. Chloramphenicol diffuses through the bacterial cell wall and reversibly binds to the bacterial 50S ribosomal subunit. The binding interferes with peptidyl transferase activity, thereby prevents transfer of amino acids to the growing peptide chains and blocks peptide bond formation. As a result bacterial protein synthesis is blocked and impede bacterial cell proliferation.

Uses

Chloramphenicol is used for the treatment caused by typhoid bacillus, dysentery bacillus, Escherichia coli, bacillus, influenza and pneumococcal infections such as brucellosis.
Chloramphenicol is used in the treatment of infections caused by bacteria. It works by killing bacteria or preventing their growth.
Chloramphenicol is used to treat serious infections in different parts of the body. It is sometimes given with other antibiotics. However, chloramphenicol should not be used for colds, flu, other virus infections, sore throats or other minor infections, or to prevent infections.
Chloramphenicol should only be used for serious infections in which other medicines do not work. This medicine may cause some serious side effects, including blood problems and eye problems. Symptoms of the blood problems include pale skin, sore throat and fever, unusual bleeding or bruising, and unusual tiredness or weakness.

You and your doctor should talk about the good this medicine will do as well as the risks of taking it .
Chloramphenicol is available only with your doctor's prescription.