High Purity API Tri...

High Purity API Triclabendazole Powder with Factory Price CAS 68786-66-3
High Purity API Triclabendazole Powder with Factory Price CAS 68786-66-3
High Purity API Triclabendazole Powder with Factory Price CAS 68786-66-3

High Purity API Triclabendazole Powder with Factory Price CAS 68786-66-3

Min.Order / FOB Price:Get Latest Price

1 Gram

FOB Price: USD 1.0000

  • Min.Order :1 Gram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,,MoneyGram

Keywords

68786-66-3 CAS 68786-66-3 Triclabendazole

Quick Details

  • Appearance:white powder
  • Application:Triclabendazole(CGA89317) is a benzimidazole, it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis.Target: Microtubule/TubulinTriclabendazole treatmen
  • PackAge:In 210kgs net steel drum or 1050kgs net IBC.
  • ProductionCapacity:100|Metric Ton|Day
  • Storage:dry and cool place
  • Transportation:special line with double clearance.

Superiority:

Triclabendazole Biological Activity

Description Triclabendazole(CGA89317) is a benzimidazole, it binds to tubulin impairing intracellular transport mechanisms and interferes with protein synthesis.Target: Microtubule/TubulinTriclabendazole treatment produces percentage decreases of the fluke egg output by 15.3%, 4.3% and 36.6%, respectively, in sheep, dairy cows and heifers, these results indicate the presence of TCBZ-resistant Fasciola hepatica in sheep and cattle on this farm [1]. Triclabendazole sulphoxide (50 mg/mL) results in extensive damage to the tegument of triclabendazole-susceptible F. hepatica, whereas triclabendazole-resistant flukes shows only localized and relatively minor disruption of the tegument covering the spines [2].Triclabendazole is metabolized into a number of compounds, depending on the route of administration, plasma levels peak at 18-24 hours (Triclabendazole sulphoxide) and 36-48 hours (Triclabendazole sulphone), neither Triclabendazole nor any toher metabolites can be detected in plasma. Triclabendazole sulphoxide blocks the transport of secretory bodies from the cell body to the tegumental surface, the block occurs at the site of their formation by the Golgi complex in the cell body, in their movement through the cytoplasmic connections to the syncytium, and in their movement from the base to the apex of the syncytium. Triclabendazole binds to the colchicine binding site on the β-tubulin molecule and this has been used at the basis for evaluating the relative acitvity of Triclabendazole [3].
Related Catalog

Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin

Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

Research Areas >> Infection

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 495.9±55.0 °C at 760 mmHg
Melting Point 175-176°C
Molecular Formula C14H9Cl3N2OS
Molecular Weight 359.658
Flash Point 253.7±31.5 °C
Exact Mass 357.950104
PSA 63.21000
LogP 5.97
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.724
Stability Stability

Details:

Company Profile

 

Wuhan Shuokang biological Technology Co., Ltd. is a professional chemical company， located in Wu Han city, Hubei Province, China. We are in the production, sales and supply pharmaceutical intermediates. In the past years, our products have spread over more 50 countries in the world. Most of products produced and sold are exported abroad, and it’s well-received in all around the world for its excellent quality. Our goal is to survive by quality and develop by credit.

In the past two years, our products have spread over more than 30 countries in the world, Europe, South America, North America,Southeast Asia and Africa. We work with friends all over the world to develop the best quality products, the most reasonable price, safe and effective transportation.

 

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FAQ

Q1: Are you a manufacturer
Answer: Yes, we are factory founded on 2011.

Q2: How to contact with us
Click the "Contact Supplier" And then send us message the product you interest in, you will get valid reply within TWO hours.

Q3:Which kind of payment terms do you accept
For small order,you can pay by T/T, or Paypal,nomal order by T/T to our company account

Q4:Can you give me a discount price
Sure,It depends on your qty.

Q5:How can i get a sample
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your
order in the future.

Q6: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the
samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q7:How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us,
we will send you free goods for replacement or refund your loss.

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