CasNo.5508-58-7,Andrographolide,(5508-58-7) Suppliers

0 Metric Ton	Negotiable

Min.Order :0 Metric Ton
Purity: 98%
Payment Terms : L/C,D/P,T/T

Keywords

Andrographolide Andrographolide high purity 5508-58-7 98%

Quick Details

Appearance:brown to white powder
Application:antiviral, anti-inflammatory, and anticancer
PackAge: 25kg/drum, double-layer plastic bags
ProductionCapacity:10|Metric Ton|Month
Storage:cool and dry place avoiding sunlight
Transportation:by sea or by air

Superiority:

We have several production sites which allow us to produce all of our products on regular basis.

We have a team of researchers and technicians, that constantly devote themselves in developing new products.

Our product quality is stable with many years of production experience accumulation.

Our sales team quotes as per client’s requirements with multilingual speakers of fast response.

We provide fast and safe delivery. We have international logistics services and can deliver services from major China ports and to client’s designated airport or even to door with custom clearing services.

We provide a range of supportive payment methods from T/T to L/C, which caters to clients with different financial situations and be as supportive as we can.

We have customized packing and reliable storage conditions. We deliver to you freshly made high quality materials and our staff are committed in meeting different packaging requirements as well.

We provide good after-sales service. If there’s any problem with receiving our products, either material-wise, package-wise or shipment-wise, you can come to our sales service team. We will not hold back in answering any questions that you have.

Details:

Andrographolide is the bitter principle, a colorless and neutral crystalline substance. It is the major labdane diterpenoid isolated from Andrographis paniculate. It exhibits antiviral, anti-inflammatory, and anticancer activities. The underlying mechanism is the inhibition of the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling (specifically p38 MAPK/ERK1/2) pathway and downstream transcription factors such as nuclear factor kappa B (NF-κB) and nuclear factor of activated T cells (NFAT). Andrographolide is also confirmed with chemopreventive effects against and the inhibitory effects on cancer cell growth in breast, colon, epidermoid, gastric, liver, leukemia, myeloma, peripheral blood lymphocytes, and prostate cancers. Andrographolide has been used for liver complaints and fever, and as an anti-inflammatory and immunostimulant. Andrographolide exerts anti-growth and pro-apoptotic effects on human rheumatoid arthritis fibroblast- like synoviocytes, the main cellular constituent of pannus, that combined with a massive infiltration of lymphocytes and macrophages, invades and destroys the local articular structure. Thereby, andrographolide is proposed to be used in Rheumatoid Arthritis and other autoimmune diseases.