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10 Gram |
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Eptifibatide Eptifibatide Acetate 148031-34-9
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Product name |
Eptifibatide acetate |
Sequence |
Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 |
CAS No. |
188627-80-7 (Eptifibatide (net)), 148031-34-9 (Eptifibatide acetate) |
Molecular Formula |
C35H49N11O9S2 |
Molecular Weight |
832.4 |
Molecule Structure |
|
Quality Standard |
98% up by HPLC, GMP |
Appearance |
White slightly yellwish powder |
|
Items |
Specification |
Results |
Appearance |
White slightly yellwish powder |
Conforms |
Purity(HPLC) |
> 98% |
99.57% |
Peptide |
≥ 80% |
|
Specific optical rotation |
-53- -57°(C=5, 1% Acetic acid) |
-55.6° |
Solubility |
Soluble in water and 1% acetic acid at a concentration of ≥ 1mg/ml to give a clear, colorless solution |
Conforms |
Related substances (HPLC) |
Total impurities: ≤ 1.5% |
0.6% 0.2% |
Water (Karl Fischer) |
≤ 5.0 % |
3.8% |
Acetic acid (HPLC) |
≤ 10.0% |
8.7% |
Bacterial endotoxins |
< 10EU/mg |
Conforms |
Mass balance |
95.0%-105.% |
98.11% |
DMF (GC) |
≤0.088% |
Conforms |
can |
≤0.041% |
Conforms |
Conclusion |
Complies with the standard. |
Function of Eptifibatide acetate
Eptifibatide acetate is a cyclic heptapeptide, a glycoprotein IIb/IIIa receptor inhibitor, and has antiplatelet activity.
Application of Eptifibatide acetate
Eptifibatide acetate is used for the treatment of acute coronary syndrome (unstable angina pectoris/non-ST-elevation myocardial infarction), including patients who will receive medical treatment or who are planning to undergo percutaneous coronary intervention (PCI).
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