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10 Gram |
Negotiable |
Goserelin Acetate Goserelin 145781-92-6
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Product name |
Goserelin Acetate |
CAS No. |
145781-92-6 |
Molecular Formula |
C59H84N18O14.C2H4O2 |
Molecular Weight |
1269.41 |
Molecule Structure |
|
Quality Standard |
98% up by HPLC, EP |
Appearance |
White slightly yellowish powder |
COA of Goserelin Acetate |
Items |
Specification |
Results |
Appearance |
White slightly yellowish powder |
Conforms |
Appearance of solution |
Clear, colorless to slightly colored solution in water(10mg/ml) |
Conforms |
Purity(HPLC) |
> 98% |
99.3% |
Peptide |
≥ 80% |
|
Amino acids |
Arg:0.9-1.1 Leu: 0.9-1.1 Tyr: 0.9-1.1 Glu: 0.9-1.1 Pro: 0.9-1.1 His: 0.9-1.1 Ser: 0.9-1.1 Trp:Detected |
1.08 1.00 0.98 1,06 1.07 1.06 0.97 Detected |
Specific optical rotation |
-52- -56°([a]20D(c=0.2 water)) |
-54.6° |
Related substances (HPLC) |
Total impurities: ≤ 2.5% |
0.9% 0.3% |
Water (Karl Fischer) |
≤ 10.0 % |
3.8% |
Acetate content (HPLC) |
≤ 4.5%-15.7% |
10.3% |
Conclusion |
Complies with the standard. |
Usage |
Function of Goserelin Acetate
Goserelin acetate is an analog of gonadotropin releasing hormone. It can inhibit ovarian function to make premenopausal women reach the level of postmenopausal hormones. At the same time, it can also protect the ovaries and follicles during chemotherapy. It protects the patient's ovaries from chemotherapy damage, restores ovarian function after stopping chemotherapy, and protects fertility. For premenopausal patients, after stopping goserelin acetate sustained-release implants, menstrual and ovarian function can be restored. At the same time, goserelin acetate is also used in prostate cancer to play a role in drug castration.
Application of Goserelin Acetate
1. Prostate cancer: This product is suitable for prostate cancer that can be treated with hormones.
2. Breast cancer: suitable for breast cancer in premenopausal and perimenopausal women who can be treated with hormones.
3. Endometriosis: Relieving symptoms includes reducing pain and reducing the size and number of endometrial damage.
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