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25 Kilogram |
Negotiable |
Isotretinoin 13-cis-Vitamin A acid Vitamin A acid
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Product name |
Isotretinoin |
CAS No. |
4759-48-2 |
Molecular Formula |
C20H28O2 |
Molecular Weight |
300.441 |
Quality Standard |
98% up by HPLC, USP |
Appearance |
Yellow crystalline powder |
|
ITEM |
SPECIFICATIONS |
RESULTS |
Description |
Yellow crystalline powder |
Yellow crystalline powder |
Identification |
The IR absorption spectrum should correspond with reference spectrum Should exhibits maximum absorption at 354nm |
Correspond with reference spectrum Exhibits maximum absorption at 354nm |
Loss on drying |
Not more than 0.5% |
0.05% |
Residue on ignition |
Not more than 0.1% |
0.02% |
Heavy metals |
Not more than 0.002% |
Less than 0.002% |
Organic volatile impurity |
Complies |
Complies |
Tretinoin |
Not more than 1.0% |
0.28% |
Assay |
98.0-102.0% (calculated on the dried basis) |
100.1% |
Conclusion: It conforms to the requirements of USP34 |
|
Function of Isotretinoin
Isotretinoin is a class of retinoic acid drugs. Its main function is to inhibit the secretion of sebaceous glands, improve sebum keratinization, and improve the symptoms of hair follicle horn plugs that block pores. Clinically, it is mainly used to treat moderate to severe acne, pimples, some keratotic skin diseases, such as psoriasis and lichen planus, etc., and can also treat some skin tumors.
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