Supply Rhubarb extract Chrysophanic acid 98% 481-74-3

Superiority:

Chrysophanol (CHR) is one of traditional Chinese medicine which was reported to show protective effects in cognition dysfunction and inflammatory in previously studies. In this current study, whether CHR protects learning and memory dysfunctions induced by diabetes disease or not and underlying mechanisms were studied.

Chrysophanic has the unique curative effect of improving glucose metabolism abnormality, reversing insulin resistance, effectively preventing diabetic nephropathy, and new pharmacodynamic characteristics. It is known to be useful for treating diabetic
nephropathy, and has good safety. The researchers conducted systematic in vitro and in vivo studies on rhein. It was found that rhein inhibits the activity of glucosamine pathway in cell sugar metabolism by inhibiting the function of glucose transporter 1 and inhibits the expression of PAI-1 in endothelial cells.
The function of endothelial cells and the mechanism of reversing insulin resistance play a role in the treatment of diabetic nephropathy, which are new mechanisms of action in the treatment of diabetic nephropathy. Its efficacy has been given in a series of animal models, such as type 1 diabetic nephropathy (STZ rat model, NOD mouse model) and type 2 diabetic nephropathy (high glucose and high fat diet model, db/db mouse model) model. verification. There is no similar international treatment for this new material for the treatment of diabetic nephropathy.