CasNo.33069-62-4,Supply Yew bark extract Paclitaxel 98%,(33069-62-4) Suppliers

10 Gram	Negotiable

Min.Order :10 Gram
Purity: 98%
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Paclitaxel 33069-62-4 Yew bark extract

Quick Details

Appearance:White powder
Application:Pharmaceutical raw materials
PackAge:25kg / cardboard barrel
ProductionCapacity:1|Metric Ton|Month
Storage:Sealed in dry,Room Temperature
Transportation: Express, air cargo and sea

Superiority:

Paclitaxel is a monomer diterpenoid extracted from the bark of Natural Plant Taxus. It is a complex secondary metabolite. It is also the only drug known to promote microtubule polymerization and stabilize polymerized microtubules. Isotope tracing showed that paclitaxel only bound to polymerized microtubules and did not react with unpolymerized tubulin dimers. After contacting paclitaxel chemicalbook, cells will accumulate a large number of microtubules in cells. The accumulation of these microtubules interferes with various functions of cells, especially stops cell division in mitotic stage and blocks normal cell division. Paclitaxel is mainly used in ovarian cancer and breast cancer through the second - and third clinical study. It also has some effect on lung cancer, colorectal cancer, melanoma, head and neck cancer, lymphoma and brain tumor.

Details:

Chemical Name: Paclitaxel
CAS No.: 33069-62-4

Chemical Structure: C47H51NO14

Molecular weight: 853.92

Appearance: White powder

Assay: 98%min

1.Antineoplastic drugs. It is used to treat metastatic breast cancer and metastatic ovarian cancer. Broad-spectrum antineoplastic botanical drugs are used to treat ovarian cancer, breast cancer and other diseases.

2.Broad-spectrum antineoplastic botanical drugs are used to treat ovarian cancer, breast cancer and other diseases.

3.Effective anti-tumor drugs; combination β- The N-terminal region of tubulin promotes highly stable microtubule formation, resists depolymerization, prevents normal cell division and capture in the G2 / M phase of the cell cycle.

4.The utility model relates to an anti microtubule drug, which can promote tubulin polymerization, inhibit depolymerization, maintain tubulin stability and inhibit cell mitosis. It acts on human endothelial cells with IC50 of 0.1 PM.

Appearance	White wax powder	Conforms
Odor	Characteristic	Conforms
Tasted	Characteristic	Conforms
Assay(Octacosanol)	98% Min	98.73%
Sieve Analysis	100% pass 60 mesh	Conforms
Loss on Drying	5% Max.	3.17%
Sulphated Ash	5% Max.	3.36%
Extract Solvent	Alcohol & Water	Conforms
Heavy Metal	5ppm Max	Conforms
As	2ppm Max	Conforms
Residual Solvents	0.05% Max.	Negative
Microbiology
Total Plate Count	10000/g Max	Conforms
Yeast & Mold	100/g Max	Conforms
E.Coli	Negative	Conforms
Salmonella	Negative	Conforms