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Quercetin 117-39-5 Sophora japonica extract
Quercetin, also known as quercetin, quercetin dissolved in glacial acetic acid, alkaline aqueous solution was yellow, almost insoluble in water, ethanol solution taste bitter. Quercetin can be used as drugs, has a good expectorant, cough effect, and some asthma. Quercetin also used for lowering blood pressure, increasing capillary resistance, reducing capillary fragility, expansion of coronary artery, Quercetin play the role of the increase in coronary blood flow. For the treatment of chronic bronchitis. Quercetin is usefull of adjuvant therapy in patients with coronary heart disease and hypertension.
Quercetin is a potent antioxadant and has anti-inflammatory activity, protecting cellular structures and blood vessels from the damading effects of free radicale. It improves blood vessel strength. Quercetin inhibits the activity of catechol-O-methyltransferase that breaks down the neurotransmitter norepinephrine. This effect may lead to elevate thelevels of norepinephrine and an increase in energy expenditure and fat oxidation. It also means quercetin acts as an antihistamine leading to the relief of allergies and asthma. As an antioxidant, it reduces LDL cholesterol and offers protection from heart diaease.
Quercetin is extracted from the Sophora flavescens Ait. Quercetin is a potent antioxidant and has anti-inflammatory activity, protecting cellular structures and blood vessels from the damaging effects of free radicals. It improves blood vessel strength. Quercetin inhibits the activity of catechol-O-methyltransferase that breaks down the neurotransmitter norepinephrine. This effect may lead to elevated levels of norepinephrine and an increase in energy expenditure and fat oxidation. As an antioxidant, it reduces LDL cholesterol and offers protection from heart disease. Quercetin blocks an enzyme that leads to accumulation of sorbitol, which has been linked to nerve, eye, and kidney damage in diabetics.
Chemical Name: Quercetin
CAS No.: 117-39-5
Chemical Structure: C15H10O7
Molecular weight: 302.24
Appearance: Light Yellow powder
Assay: 98%min
1.Quercetin may expel phlegm and arrest coughing, it can also be used as anti-asthmatic.
2. Quercetin has anticancer activity, inhibits PI3-kinase activity and slightly inhibits PIP Kinase activity, reduces cancer cell growth via type II estrogen receptors.
3. Quercetin may inhibit histamine release from basophils and mast cells.
4. Quercetin may control the spread of certain viruses within the body.
5. Quercetin may help reduce tissue destruction.
6. Quercetin may also be beneficial in the treatment of dysentery, gout, and psoriasis.
1. Quercetin Pharmaceutical industry: Some medicine with bromelain like throat tablet can diminish inflammation, facilitate digestion and improve immunological competence.So it can be applied in examination, treatment of gynecopathy, glaucoma and inset bitten.
2. Quercetin Food industry: It can be applied in hydrolyzing protein of plants and animals, so it can be used in the meat tenderizer,wine clarifier,stabilizer of noodle,health foods and soy sauce brewing etc. It can also improve the nutritional value.
TEST |
SPECIFICATION |
RESULTS |
TEST METHOD |
Appearance Identification Melting point Particle size Bulk density Tapped Density Heavy metals -Arsenic(As) -Lead (Pb) -Mercury(Hg) -Cadmium(Cd) Sulphated Ash Loss on drying Assay by HPLC |
Yellow powder Must positive 305℃—315℃ 95% pass through Sieve # 80 mesh ≥0.20gm/cc ≥0.30gm/cc ≤10ppm ≤2ppm ≤2ppm ≤1ppm ≤1ppm ≤0.30% ≤12.0% ≥95.0% |
Complies Positive 312℃ Complies 0.23gm/cc 0.34gm/cc 5ppm 0.46ppm 0.52ppm 0.06ppm 0.08ppm 0.23% 9.5% 95.75% |
Visual Infrared Absorption Melting point Apparatus CP2010 CP2010 CP2010 Atomic Absorption Atomic Absorption Atomic Absorption Atomic Absorption Atomic Absorption CP2010 5g/120℃ HPLC |
Microbiological test: Total plate count Mildew & Yeast E.Coli Salmonella Staphylococcus |
≤1000cfu/g ≤300cfu/g Negative Negative Negative |
100 cfu/g 10cfu/g Complies Complies Complies |
CP2010 CP2010 CP2010 CP2010 CP2010 |
Residual Solvent Pesticide Screen |
≤0.5% Not Detected |
Complies Complies |
GC GC |
Packing&Storage
Shelf Life |
Packed in paper-drums and two plastic-bags inside.N.W.:25kgs Store in a well-closed containers,in a cool dry area. Two years if sealed and stored away from direct sun light and heat. |
||
Conclusion |
The test results conform to Quercetin Dihydrate HPLC 95% standard. |
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