Cystathionine β-synthase

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1 Gram	Negotiable

1 Gram

Negotiable

Min.Order :1 Gram
Purity: ≥95%
Payment Terms : T/T

Keywords

HCY assay reagents biochemical raw material homocysteine test

Quick Details

Appearance:yellow amorphous freeze-dried powder
Application:Cystathionine β-lyase is an enzyme that breaks down cystathionase. There are two kinds of β-cystathionase and γ-cystathionase. Both types use pyridoxal phosphate as a coenzyme. β-cystathionase dec
PackAge:
ProductionCapacity:|Metric Ton|Day
Storage:-20°C
Transportation:Cold Chain Shipping with Dry Ice

Superiority:

Comes in a freeze-dried powdered form;

Features a modified molecular structure with higher stability and water solubility;

Simplify the process of reagent preparation by the accurate activity of CBS, reduced the difference batch to batch.

Details:

Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. It catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine:

L-serine + L-homocysteine {\displaystyle \rightleftharpoons } $\rightleftharpoons$ L-cystathionine + H₂O

CBS uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds.

CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The CBS gene is the most common locus for mutations associated with homocystinuria.

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