Supply Artemisia an...

Supply Artemisia annua extract Artesunate 98% 88495-63-0
Supply Artemisia annua extract Artesunate 98% 88495-63-0
Supply Artemisia annua extract Artesunate 98% 88495-63-0
Supply Artemisia annua extract Artesunate 98% 88495-63-0
Supply Artemisia annua extract Artesunate 98% 88495-63-0

Supply Artemisia annua extract Artesunate 98% 88495-63-0

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 98%
  • Payment Terms : L/C,D/A,D/P,T/T

Keywords

Artesunate 88495-63-0 Artemisia annua extract

Quick Details

  • Appearance:white powder
  • Application:Pharmaceutical raw materials
  • PackAge:25kg / cardboard barrel
  • ProductionCapacity:1|Metric Ton|Month
  • Storage:Sealed in dry,Room Temperature
  • Transportation: Express, air cargo and sea

Superiority:

Artesunate is a rapid insecticide against Plasmodium falciparum in the erythrocytic stage of Plasmodium falciparum. It can quickly control the acute attack of malaria after taking it. it is used for the rescue of dangerous malaria such as brain type, jaundice type and the treatment of falciparum malaria.
Artesunate is a commonly used antiparasitic drug, which is a derivative of artemisinin with sesquiterpene lactone structure to reduce artemisinin succinate. it has a stronger effect on Plasmodium than artemisinin and is effective against chloroquine strains. Acting on the erythrocytic merozoite of Plasmodium Chemicalbook, artemisinin inhibits cytochrome oxidase by reducing artemisinin to inhibit the cytochrome oxidase of plasmodium surface membrane-food vesicle and mitochondrial membrane, thus blocking the supply of host cytoplasm as nutrition.

Details:

Chemical Name: Artesunate
CAS No.: 88495-63-0

Chemical Structure: C19H28O8

Molecular weight: 384.42

Appearance: white powder

Assay: 98%min

Artemisia Annua Extract Powder also known as Qinghaosu (Chinese), and its derivatives are a group of drugs that possess the most rapid action of all current drugs against Plasmodium falciparum malaria.Treatments containing an artemisinin derivative (artemisinin-combination therapies, ACTs) are now standard treatment worldwide for P. falciparum malaria. The starting compound artemisinin is isolated from the plant Artemisia annua, sweet wormwood, an herb employed in Chinese traditional medicine.

Chemically, artemisinin is a sesquiterpene lactone containing an unusual peroxide bridge. This peroxide is believed to be responsible for the drug's mechanism of action. Few other natural compounds with such a peroxide bridge are known.(Ascaridole isanother.)

Use of the drug by itself as a monotherapy is explicitly discouraged by the World Health Organization, as there have been signs that malarial parasites are developing resistance to the drug. Therapies that combine artemisinin with some other antimalarial drug are the preferred treatment for malaria and are both effective and well tolerated in patients. The drug is also increasingly being used in Plasmodium vivax malaria,[3] as well as being a topic of research in cancer treatment.

 

1. It has a strong killing effect on the asexual body of Plasmodium, and can quickly control the outbreak of malaria.


2.Antimalarial drug.


3. Artesunate is a semisynthetic artemisinin derivative that has been shown to be effective against parasites such as liver fluke (liver flukes) and has cytotoxic effects on different types of tumor cell lines.

Item

 

Specification

 

Analytical Result

 

Apperance

 

White crystalline powder,odorless

 

Conforms

Solubility

Free soluble in ethanol,acetone or chloroform,very slightly solyble in water

Conforms

Specific optical rotation

+4.5°~6.5°

+5.3°

Identification

 

 

TLC

The pronciopal spot in the chromatogram obtained with the test solution is similar in posotion,colour

to the principal spot in the chromatogram obtained the reference solution

 

Conforms

HPLC

The retention time of main peak of test and standard are concordant

Conforms

 

IR

Infrared absorption spectrum of test and

standard(or infrared reference spectra No.221) are concordant

 

Conforms

Tests

 

Acidity

3.5-4.5

4.3

 

 

Apperance of solution

 

Solution S is clear and not more intensely colored than reference solution 1

 

 

Conforms

 

Chlorieds

 

Not more than pronounced (0.02%)

 

Conforms


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