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Yohimbine hydrochloride 65-19-0 Corynante Yohimbe extract
Yohimbine hydrochloride (molecular structure formula c21h26n2o3hcl, yohimbine hydrochloride in English) is also known as weibizhi, yohimbine hydrochloride, yohimbine base, solanide tablets and solanide. It is white to milky white fine powder in appearance, slightly fragrant, bitter and astringent in taste, melting point 288 ℃ ~ 290 ℃, easily soluble in chloroform, methanol, ethanol and slightly soluble in water. The plant comes from the dried bark of the wild African plant corynante Yohimbe or the extract of the bark of the West African plant Rubiaceae Conan. The pharmacological effect is to increase muscle tone and inhibit urine without damage; Accelerate body energy metabolism and increase energy supply. Clinical single dose is used to treat male impotence and sexual dysfunction. The mechanism of action is that it can selectively block presynaptic α 2 receptor, promote the release of norepinephrine, release more norepinephrine from the ends of cavernous nerve, reduce the reflux of penile vein, facilitate congestion and erection, and increase sexual fluid secretion. When applied in a small amount, it can swell the perineum, stimulate the erectile center of spinal cord and make sexual function hyperactive.
Chemical Name: Yohimbine hydrochloride
CAS No.: 65-19-0
Chemical Structure: C21H27ClN2O3
Molecular weight: 390.9
Appearance: white powder
Assay: 98%min
Yohimbine is a mild inhibitor of monoamine oxidase and has the effects of aphrodisiac and stimulant. It is sold as a medical prescription drug for the treatment of sexual dysfunction. Yohimbine is also carried α 2A adrenoceptor gene polymorphism is an exploration drug for human and animal models of type 2 diabetes treatment.
Yohimbine is a mild inhibitor of monoamine oxidase and has the effects of aphrodisiac and stimulant. It is sold as a medical prescription drug for the treatment of sexual dysfunction. Yohimbine is also carried α 2A adrenoceptor gene polymorphism is an exploration drug for human and animal models of type 2 diabetes treatment.
ITEM |
SPECIFICATION |
METHOD |
Physical Description |
||
Appearance |
White Powder |
Visual |
Odor |
Characteristic |
Organoleptic |
Taste |
Characteristic |
Olfactory |
Particle size |
95%-99%% through 80 mesh |
CP2015 |
Chemical Tests |
||
Yohimbine HCL |
≥98% |
HPLC |
Loss on drying |
≤1.0% |
CP2015 (105 oC, 3 h) |
Ash |
≤1.0 % |
CP2015 |
Total Heavy Metals |
≤10 ppm |
CP2015 |
Cadmium (Cd) |
≤1 ppm |
CP2015(AAS) |
Mercury (Hg) |
≤1 ppm |
CP2015(AAS) |
Lead (Pb) |
≤2 ppm |
CP2015(AAS) |
Arsenic (As) |
≤2ppm |
CP2015(AAS) |
Microbiology |
||
Total plate count |
≤1000 CFU/g |
Complies |
Yeast & mold |
≤100 CFU /g |
Complies |
E.coli |
Negative |
Negative |
Salmonella |
Negative |
Negative |
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