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Tranexamic Acid 1197-18-8 cyclocapron
Tranexamic Acid is a synthetic amino acid that functions as a skin-conditioning agent and astringent. In cosmetics, it functions on skin as a barrier repair ingredient and seems able to help skin recover from damage. It an effective skin lightener when used in cosmetic formulations.
Tranexamic acid is a protease inhibitor, can inhibit protease catalyzed peptide bond hydrolysis, so as to prevent such as the primary protease activity, thereby inhibiting the skin black cell dysfunction, and inhibit the melanin enhancement factor group, its effect of blackening and spot removal is about 50 times higher than vitamin C, is about 10 times that of fruit acid.
Chemical Name: Tranexamic Acid
CAS No.: 1197-18-8
Chemical Structure: C8H15NO2
Molecular weight: 157.21
Appearance: White powder
Assay: 98%min
1. Trauma: Tranexamic Acid Powder has been found to decrease the risk of death in people who have significant bleeding due to trauma.
2. Heart surgery: Tranexamic Acid is commonly used in cardiac surgery, both with and without cardiopulmonary bypass.
3.Orthopedic surgery: Tranexamic Acid Powder is used in orthopedic surgery to reduce bloodloss.
4. Menstrual bleeding:Used as firstline nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids.
5.Dentistry: Tranexamic Acid Powder is used in dentistry in the form of a 5% mouth rinse after extractions or surgery in patients with prolonged bleeding time, e.g. from acquired or inherited disorders.
6.In hemophilia: Tranexamic Acid Powder is also useful in the treatment of bleeding as a second line treatment after factor VIII in patients (e.g. tooth extraction).
7.Whitening effect: Clinical studies for years have proved that tranexamic acid can dilute spot effectively and rapidly, which helps to demonstrate a perfect white and bright skin. The spot-removing effect of tranexamic acid is about 50 times over Vitamin C, and 10 times over AHA. The concentration limit of usage is 2%-3%, and in cosmetics the amount is around 0.5%.
8.Tranexamic Acid Powder is used for Comestics,freckle whitening an so on.
1) It has definite curative effect on chloasma.
2)Effectively dilute acne marks, red blood and purple spots.
3) Moisturizing and hydrating, whitening skin.
Items | Standards |
Characters | White or almost white, crystalline powder |
Solubility | Freely soluble in water and in glacial acetic acid, practically insoluble in acetone and 95% alcohol |
Identification | Infraredabsorption atlasconsistent with the contract atlas |
Clarity and color | Solution should clarify and colorless |
PH | 7.0-8.0 |
Related substances liquid chromatography(2.2.29) | Impurity A: 0.1%maxImpurity B:0.2%maxAny other impurity: 0.1%maxAll other impurity: 0.2%max |
Chlorides | 140ppm max |
Heavy Metals | 10ppm max |
Loss on drying | 0.5%max |
Sulphated ash | 0.15 max |
Assay | 99.0~101.0% |
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