FLONICAMIDCAS NO.15...

FLONICAMIDCAS NO.158062-67-0

FLONICAMIDCAS NO.158062-67-0

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Keywords

FLONICAMID N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide

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  • ProductionCapacity:10000|Metric Ton|Month
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Details:

Product Name: FLONICAMID
Synonyms: N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide;flonicamid (bsi, pa iso);iki-220;FLONICAMID STANDARD;flonicamid、flunicotamid;3-Pyridinecarboxamide, N-(cyanomethyl)-4-(trifluoromethyl)-;Aria;F 1785
CAS: 158062-67-0
MF: C9H6F3N3O
MW: 229.16
EINECS:  
Product Categories:  
Mol File: 158062-67-0.mol
FLONICAMID Structure
 
FLONICAMID Chemical Properties
Melting point  157.5°
Boiling point  406.6±45.0 °C(Predicted)
density  1.377±0.06 g/cm3(Predicted)
pka 10.99±0.46(Predicted)
form  neat
EPA Substance Registry System Flonicamid (158062-67-0)
 
Safety Information
Hazard Codes  Xn
Risk Statements  22
WGK Germany  2
HS Code  29333990
Hazardous Substances Data 158062-67-0(Hazardous Substances Data)
Toxicity LD50 in male, female rats (mg/kg): 884, 1768 orally; in rats (mg/kg): >5000 dermally; in rats (mg/m3): >4900 by inhalation; LC50 in carp, rainbow trout (mg/l): >100, >91.9 (Morita)
MSDS Information
 
FLONICAMID Usage And Synthesis
Description Flonicamid is a pyridinecarboxamide insecticide. It inhibits the brown planthopper (N. lugens) inward-rectifying potassium channel Kir1 (IC50 = 0.64 μM). Flonicamid (100 μg/ml) inhibits aphid (M. persicae) salivation and sap ingestion during feeding on Japanese radish leaves. It induces toxicity in the aphid species A. gossypii, R. padi, S. graminum, and L. erysimi (LC50s = 0.64, 0.74, 0.78, and 2.01 μg/ml, respectively) and rats (LD50 = ≥844 mg/kg). Formulations containing flonicamid have been used for the control of pest insects in agriculture.
Uses Flonicamid is an novel insecticide with rapid inhibitory effect against aphid feeding.
Uses Insecticide.
Uses Flonicamid is a novel insecticide with rapid inhibitory effect against aphid feeding. Useful in cannabis testing kits as a component of pesticide mixes (P698240).
Definition ChEBI: A pyridinecarboxamide that is nicotinamide substituted by a trifluoromethyl group at position 4 and a cyanomethyl group at the carbamoyl nitrogen atom.
Application With foliar spray application at the rates of 50-100 g a.i./ha, onicamid exhibits excellent aphicidal activity and also shows good insecticidal activity against other sucking insect pests such as thrips, whiteies, planthoppers, leafhoppers, plant bugs, and mealybugs in fruit trees, cereals, rice, potatoes, cotton, vegetables and ornamentals. Flonicamid soil applications also provide control of the foliar pests mentioned above.
Definition Flonicamid is a chordotonal modulator and novel systemic insecticide that has been used frequently for controlling a broad range of insect pests. The risk of flonicamid resistance was assessed through laboratory selection and determining inheritance pattern and cross-resistance potential to five insecticides in house fly, Musca domestica L. Very low to high flonicamid resistance in M. domestica populations was found compared with the susceptible strain (SS).
Mode of action Flonicamid rapidly inhibits the feeding behavior of aphids, and has better action through ingestion than by contact. Its mode of action is different from other insecticides such as neonicotinoids, pymetrozine and pyriuquinazon. Flonicamid belongs to IRAC Group 29 and is the only insecticide in this class.

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