CasNo.100643-71-8,Best price& High quality desloratadine CAS NO.100643-71-8,(100643-71-8) Suppliers

1 Kilogram	FOB Price:USD 10.0000 -160.0000

Min.Order :1 Kilogram
Purity: 99%
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Keywords

100643-71-8 desloratadine AzoMyr

Quick Details

Appearance:White powder
Application:Pharmaceutical Intermediate
PackAge:1kg/bag, 25kg/drum, Standard export packing or as clients'requirement packing
ProductionCapacity:500|Metric Ton|Month
Storage:Keep in dark place,Sealed in dry Room
Transportation:express:dhl,tnt,ups,fedex and ems

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Package & Delivery

Packing: 1kg/bag, 25kg/drum, Standard export packing or as clients'requirement packing
Express: EMS/ DHL/ FedEx/ TNT/ UPS
Delivery: Within 3-10 days upon receipt of your payment.

Details:

Product Name:

Desloratadine

Melting point	150-151°C
Boiling point	467.9±45.0 °C(Predicted)
density	1 +-.0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: >10mg/mL
pka	10.27±0.20(Predicted)
form	powder
Merck	14,2922
InChIKey	JAUOIFJMECXRGI-UHFFFAOYSA-N
CAS DataBase Reference	100643-71-8(CAS DataBase Reference)

Boiling point	416.3±45.0 °C(Predicted)
density	1.25±0.1 g/cm3(Predicted)
pka	pKa 9.48±0.04(H2O I > 0)(Approximate)
Water Solubility	<0.1g/L(room temperature)
CAS DataBase Reference	79617-96-2(CAS DataBase Reference)
NIST Chemistry Reference	Sertraline(79617-96-2)
EPA Substance Registry System	Sertraline (79617-96-2)

Desloratadine is an antihistamine used to relieve allergy symptoms such as watery eyes, runny nose, itching eyes/nose, sneezing, hives, and itching. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction.
Application & Function
Desloratadine is a tricyclic H1-antihistamine that is used to treat allergies. It is an active metabolite of loratadine.Desloratadine is used to treat allergic rhinitis and nasal congestion.It is the major metabolite of loratadine and the two drugs are similar in safety and effectiveness.Desloratadine is available in many dosage forms and under many trade names worldwide.
An emerging indication for desloratadine is in the treatment of acne, as an inexpensive adjuvant to isotretinoin and possibly as maintenance therapy or monotherapy.
Desloratadine is a selective H1-antihistamine which functions as an inverse agonist at the histamine H1 receptor;
It is also an antagonist at all subtypes of the muscarinic acetylcholine receptors.
It exhibits only peripheral activity since it does not readily cross the blood-brain barrier; hence, it does not cause drowsiness because it does not readily enter the central nervous system.
It has a long-lasting effect and is effective in moderate and low doses.

ShuoKang biotechnology co., LTD. Is located in wuhan, China,is mainly engaged in fine chemicals and pharmaceutical intermediates, always adhere to the "market-oriented, based on quality, to manage as the carrier, to the benefit for the purpose of" the management policy, carry out customer oriented business philosophy, advocates the spirit of excellence, pioneering and innovative work, to provide customer satisfaction of chemical products, through the company all staff's hard work and honesty, won the praise and trust of customers at home and abroad, and domestic and foreign customers to establish long-term stable business relations. The product specification is complete, the quality is stable, the after-sales service is considerate, the reputation is reliable.