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Tacrolimus 104987-11-3 Tacrolimus powder
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1. The information of Tacrolimus CAS 104987-11-3
Product Name | Tacrolimus |
CAS | 104987-11-3 |
Molucular Formular | C44 H69 N O12 |
Molecular Weight | 804.02 |
2. The COA of Tacrolimus CAS 104987-11-3
3. The Use of Tacrolimus CAS 104987-11-3
Tacrolimus is a macrolide isolated from streptomycetes. It has strong immunosuppressive effect, can specifically bind and inhibit calmodulin phosphatase activity, inhibit il-2 signal transcription, and thus inhibit T cell activation, ChemicalbookTNF-α, il-1 β and il-6 production, and T cell-dependent B cell proliferation.Tacrolimus inhibited T cell activation more strongly and had fewer adverse reactions than cyclosporin, another calmodulin phosphatase inhibitor.
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