peptide Cyclic Peptides cyclo(RGDyC)
An RGD tumor-targeting peptide, which binds to αvβ3 receptors. It can be easily conjugated to fluorophore tags, chelators, or carriers. Palecek et al. converted the ε-amino group into the azide by diazo transfer allowing further functionalization by click chemistry. Mercapto groups can be introduced via acylation of this peptide with S-acetylthio- acetic acid (SATA).
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