In addition to being a buffer, what else does Tris do?

Details:

As a common biological buffer, Tris is not only widely used as a solvent for nucleic acids and proteins, but also one of the main components of protein electrophoresis buffers. In addition, Tris can also produce a variety of cosmetics, chemicals, pesticides, pharmaceuticals, paint preparation and other products, and is an important intermediate for the preparation of surfactants, vulcanization accelerators, reducing agents and some drugs.

1. Used as a drug: As commonly used in acute metabolic and respiratory acidemia, Tris base is an amino acid buffer, which can absorb hydrogen ions to correct acidosis.
2. For synthesis: Tris is used to prepare intermediates of surfactants, vulcanization accelerators and some drugs. Because it has three hydroxyl groups of equal status, it can also be used as a good reducing agent. Under the alkaline condition of sodium hydroxide, the chloroauric acid solution can be reduced to prepare stable gold nanoparticles. This method is non-toxic and non-polluting, and belongs to the green reduction method.
3. Tris as reducing agent: Under alkaline conditions, relatively stable gold nanoparticles can be obtained by reducing chloroauric acid solution by ultrasonic without adding other stabilizers. An environmentally friendly and biocompatible gold nanoparticle synthesis was achieved. By adjusting the experimental conditions, gold nanoparticles of different sizes can be prepared.
4. Neutralizer: The most common role of TRIS in cosmetics is to adjust PH value (acidity and alkalinity), and it can also be used as a neutralizer to neutralize thickeners (carbomers) to reduce stickiness and improve skin. Cellular respiration efficiency, preventing pore clogging. In addition, TRIS can be used as an odor modifier in cosmetics containing amine salts, regulating the odor of amines generated by friction when applying cosmetics, thereby avoiding the release of any residual or persistent odor.
5. Coating preparation: Tris mainly plays the following four functions in the coating preparation process: pH adjuster, cross-linking accelerator, polyester coating raw material and phase change core material.
Desheng has 15 years of rich experience in R&D and production of biological buffers, blood collection tube additives, chromogenic reagents, and chemiluminescence reagents, and can provide high-quality Tris product raw materials. In addition to Tris, the biological buffer series also includes HEPES, CAPS, MOPS, and PIPES. Now the company is actively expanding into new fields. It can provide nucleic acid detection raw material virus preservation solution and disposable gel raw material carbomer. If you need it, you can call for detailed consultation.