Factory supply Dihy...

Factory supply Dihydrocapsaicin CAS 19408-84-5
Factory supply Dihydrocapsaicin CAS 19408-84-5
Factory supply Dihydrocapsaicin CAS 19408-84-5
Factory supply Dihydrocapsaicin CAS 19408-84-5
Factory supply Dihydrocapsaicin CAS 19408-84-5

Factory supply Dihydrocapsaicin CAS 19408-84-5

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50 Kilogram

FOB Price: USD 1.0000

  • Min.Order :50 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Dihydrocapsaicin Dihydrocapsaicin Dihydrocapsaicin

Quick Details

  • Appearance:white powder
  • Application:Dihydrocapsaicin has been used as a reference standard for the identification of dihydrocapsaicin in blood and tissue samples by high performance liquid chromatography (HPLC) combined with tandem mass
  • PackAge:25KG/Drum
  • ProductionCapacity:50|Metric Ton|Month
  • Storage:2-8°C
  • Transportation:By air /Sea/ coruier

Superiority:

Dihydrocapsaicin Basic information
Product Name: Dihydrocapsaicin
Synonyms: CAPSAICINE;CAPSAICIN, NATURAL;(E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE;(E)-CAPSAICIN;(E)-N-([4-HYDROXY-3-METHOXYPHENYL]METHYL)8-METHYL-6-NONEAMIDE;FEMA 3404;FEMA 2787;N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6E-NONENAMIDE
CAS: 19408-84-5
MF: C18H29NO3
MW: 307.43
EINECS: 606-308-7
Product Categories: chemical reagent;pharmaceutical intermediate;Amines;Aromatics;Drug Analogues;phytochemical;Miscellaneous Natural Products;Intermediates & Fine Chemicals;Pharmaceuticals;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;API
Mol File: 19408-84-5.mol
Dihydrocapsaicin Structure
 
Dihydrocapsaicin Chemical Properties
Melting point  62-65 °C(lit.)
Boiling point  497.4±35.0 °C(Predicted)
density  1.026±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
solubility  H2O: insoluble
pka 9.76±0.20(Predicted)
form  White to off-white solid.
BRN  2815150
InChIKey XJQPQKLURWNAAH-UHFFFAOYSA-N
CAS DataBase Reference 19408-84-5(CAS DataBase Reference)
EPA Substance Registry System Dihydrocapsaicin (19408-84-5)
 
Safety Information
Hazard Codes  T
Risk Statements  25-37/38-41-42/43-36/37/38
Safety Statements  22-26-28-36/39-45-36/37/39
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  RA8530000
F  10-21
HazardClass  6.1(a)
PackingGroup  II
HS Code  29399990
MSDS Information
Provider Language
SigmaAldrich English
 
Dihydrocapsaicin Usage And Synthesis
Description Dihydrocapsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It is active against E. faecalis, B. subtilis, S. aureus, P. aeruginosa, K. pneumoniae, E. coli, and C. albicans (MICs = 0.6-10 μg/ml). Dihydrocapsaicin scavenges DPPH (Item No. 14805) and ABTS (Item No. 27317) radicals in cell-free assays. It increases LC3-II, a marker of autophagy, and catalase levels and reduces reactive oxygen species (ROS) production in normal WI38 lung fibroblasts and H1299, but not A549 or H460, lung cancer cells when used at a concentration of 200 μM. Dihydrocapsaicin is an agonist of transient receptor potential vanilloid 1 (TRPV1) and inhibits NETosis induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in isolated human neutrophils. It induces cortical and systemic hypothermia and reduces infarct volume in a rat model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO) when administered at a dose of 0.5 mg/kg, i.p.
Chemical Properties White Solid
Uses

Dihydrocapsaicin has been used as a reference standard for the identification of dihydrocapsaicin in blood and tissue samples by high performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS) and in tomato-based salsas by enzyme immunoassay (EIA) and LC with fluorescent detection.
It may be used as a reference standard for the determination of dihydrocapsaicin in Capsicum fruit samples by HPLC equipped with a Surveyor photodiode array (PDA) detector and in rat plasma by HPLC-triple quadrupole MS with electrospray ionization (ESI) in selected reaction monitoring (SRM) mode.
Uses Capsaicin (C175680) analog. A VR1 vaniloid receptor agonist.
General Description

Dihydrocapsaicin belongs to the capsaicinoid group of compounds which are responsible for the pungency of capsicum fruits.
Biochem/physiol Actions VR1 vanilloid receptor agonist.

Details:

Dihydrocapsaicin Basic information
Product Name: Dihydrocapsaicin
Synonyms: CAPSAICINE;CAPSAICIN, NATURAL;(E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE;(E)-CAPSAICIN;(E)-N-([4-HYDROXY-3-METHOXYPHENYL]METHYL)8-METHYL-6-NONEAMIDE;FEMA 3404;FEMA 2787;N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6E-NONENAMIDE
CAS: 19408-84-5
MF: C18H29NO3
MW: 307.43
EINECS: 606-308-7
Product Categories: chemical reagent;pharmaceutical intermediate;Amines;Aromatics;Drug Analogues;phytochemical;Miscellaneous Natural Products;Intermediates & Fine Chemicals;Pharmaceuticals;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;API
Mol File: 19408-84-5.mol
Dihydrocapsaicin Structure
 
Dihydrocapsaicin Chemical Properties
Melting point  62-65 °C(lit.)
Boiling point  497.4±35.0 °C(Predicted)
density  1.026±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
solubility  H2O: insoluble
pka 9.76±0.20(Predicted)
form  White to off-white solid.
BRN  2815150
InChIKey XJQPQKLURWNAAH-UHFFFAOYSA-N
CAS DataBase Reference 19408-84-5(CAS DataBase Reference)
EPA Substance Registry System Dihydrocapsaicin (19408-84-5)
 
Safety Information
Hazard Codes  T
Risk Statements  25-37/38-41-42/43-36/37/38
Safety Statements  22-26-28-36/39-45-36/37/39
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS  RA8530000
F  10-21
HazardClass  6.1(a)
PackingGroup  II
HS Code  29399990
MSDS Information
Provider Language
SigmaAldrich English
 
Dihydrocapsaicin Usage And Synthesis
Description Dihydrocapsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It is active against E. faecalis, B. subtilis, S. aureus, P. aeruginosa, K. pneumoniae, E. coli, and C. albicans (MICs = 0.6-10 μg/ml). Dihydrocapsaicin scavenges DPPH (Item No. 14805) and ABTS (Item No. 27317) radicals in cell-free assays. It increases LC3-II, a marker of autophagy, and catalase levels and reduces reactive oxygen species (ROS) production in normal WI38 lung fibroblasts and H1299, but not A549 or H460, lung cancer cells when used at a concentration of 200 μM. Dihydrocapsaicin is an agonist of transient receptor potential vanilloid 1 (TRPV1) and inhibits NETosis induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in isolated human neutrophils. It induces cortical and systemic hypothermia and reduces infarct volume in a rat model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO) when administered at a dose of 0.5 mg/kg, i.p.
Chemical Properties White Solid
Uses

Dihydrocapsaicin has been used as a reference standard for the identification of dihydrocapsaicin in blood and tissue samples by high performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS) and in tomato-based salsas by enzyme immunoassay (EIA) and LC with fluorescent detection.
It may be used as a reference standard for the determination of dihydrocapsaicin in Capsicum fruit samples by HPLC equipped with a Surveyor photodiode array (PDA) detector and in rat plasma by HPLC-triple quadrupole MS with electrospray ionization (ESI) in selected reaction monitoring (SRM) mode.
Uses Capsaicin (C175680) analog. A VR1 vaniloid receptor agonist.
General Description

Dihydrocapsaicin belongs to the capsaicinoid group of compounds which are responsible for the pungency of capsicum fruits.
Biochem/physiol Actions VR1 vanilloid receptor agonist.

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