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China Biggest Factory & Manufacturer supply Tetrahydrocurcumin 500MT/Year
China Biggest Factory & Manufacturer supply Tetrahydrocurcumin 500MT/Year
China Biggest Factory & Manufacturer supply Tetrahydrocurcumin 500MT/Year
China Biggest Factory & Manufacturer supply Tetrahydrocurcumin 500MT/Year
China Biggest Factory & Manufacturer supply Tetrahydrocurcumin 500MT/Year

China Biggest Factory & Manufacturer supply Tetrahydrocurcumin 500MT/Year

Min.Order / FOB Price:Get Latest Price

50 Kilogram

FOB Price:USD 1.0000 -2.0000
  • Min.Order :50 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Tetrahydrocurcumin 36062-04-1 Tetrahydrocurcumin

Quick Details

  • Appearance:white powder
  • Application:chemicals industry
  • PackAge:25KG/Drum
  • ProductionCapacity:50|Metric Ton|Month
  • Storage:2-8°C
  • Transportation:By air /Sea/ coruier

Superiority:

Tetrahydrocurcumin Basic information
Product Name: Tetrahydrocurcumin
Synonyms: SabiWhite-;3,5-Heptanedione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-;1,7-bis(4-hydroxy-3-methoxy-phenyl)heptane-3,5-dione;Tetrahydrocurcumin;TETRAHYDROCURCUMINOID;Tetrahydrodiferuloylmethane;Aids110028;Aids-110028
CAS: 36062-04-1
MF: C21H24O6
MW: 372.41
EINECS: 609-201-3
Product Categories: Aromatics;Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File: 36062-04-1.mol
Tetrahydrocurcumin Structure
 
Tetrahydrocurcumin Chemical Properties
Melting point  95-97 ºC
Boiling point  564.1±45.0 °C(Predicted)
density  1.222
Fp  196℃
storage temp.  Inert atmosphere,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly, Heated)
pka 9.12±0.10(Predicted)
form  powder
BRN  3485469
Stability: Light Sensitive
InChIKey LBTVHXHERHESKG-UHFFFAOYSA-N
 
Safety Information
WGK Germany  3
MSDS Information
 
Tetrahydrocurcumin Usage And Synthesis
Description Tetrahydrocurcumin is a metabolite of curcumin (Item Nos. 81025 | 81025.1) that has diverse biological activities, including antioxidant, anti-inflammatory, anti-angiogenic, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay with an EC50 value of 16.8 μM. Tetrahydrocurcumin (50 μM) inhibits LPS-induced increases in inducible nitric oxide synthase (iNOS) and COX-2 expression in RAW 264.7 cells. It also inhibits LPS-induced increases in TNF-α release when used at a concentration of 100 μM and increases in nitric oxide (NO) production and IL-6 levels in a concentration-dependent manner. Tetrahydrocurcumin reduces carrageenan-induced paw edema in rats (ED50 = 20 mg/kg). It also reduces the formation of neocapillaries and decreases microvascular density as well as VEGF, VEGF receptor 2 (VEGFR2), and hypoxia-inducible factor-1α (HIF-1α) expression in a CaSki cervical cancer nude mouse xenograft model when administered at doses of 100, 300, and 500 mg/kg.
Chemical Properties Yellow Solid
Uses Tetrahydro Curcumin is a major metabolite of Curcumin (C838500) that has been shown to have protective effects against diabetes and vascular dysfunction via alleviation of oxidative stress.
Definition ChEBI: A beta-diketone that is curcumin in which both of the double bonds have been reduced to single bonds.
 
Tetrahydrocurcumin Preparation Products And Raw materials
Raw materials Curcumin-->Ferulic Acid-->3,5-Heptanedione, 1,7-bis[4-(acetyloxy)-3-methoxyphenyl]--->3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID-->Vanillin

 

Details:

 

 

Tetrahydrocurcumin Basic information
Product Name: Tetrahydrocurcumin
Synonyms: SabiWhite-;3,5-Heptanedione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-;1,7-bis(4-hydroxy-3-methoxy-phenyl)heptane-3,5-dione;Tetrahydrocurcumin;TETRAHYDROCURCUMINOID;Tetrahydrodiferuloylmethane;Aids110028;Aids-110028
CAS: 36062-04-1
MF: C21H24O6
MW: 372.41
EINECS: 609-201-3
Product Categories: Aromatics;Inhibitors;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File: 36062-04-1.mol
Tetrahydrocurcumin Structure
 
Tetrahydrocurcumin Chemical Properties
Melting point  95-97 ºC
Boiling point  564.1±45.0 °C(Predicted)
density  1.222
Fp  196℃
storage temp.  Inert atmosphere,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly, Heated)
pka 9.12±0.10(Predicted)
form  powder
BRN  3485469
Stability: Light Sensitive
InChIKey LBTVHXHERHESKG-UHFFFAOYSA-N
 
Safety Information
WGK Germany  3
MSDS Information
 
Tetrahydrocurcumin Usage And Synthesis
Description Tetrahydrocurcumin is a metabolite of curcumin (Item Nos. 81025 | 81025.1) that has diverse biological activities, including antioxidant, anti-inflammatory, anti-angiogenic, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay with an EC50 value of 16.8 μM. Tetrahydrocurcumin (50 μM) inhibits LPS-induced increases in inducible nitric oxide synthase (iNOS) and COX-2 expression in RAW 264.7 cells. It also inhibits LPS-induced increases in TNF-α release when used at a concentration of 100 μM and increases in nitric oxide (NO) production and IL-6 levels in a concentration-dependent manner. Tetrahydrocurcumin reduces carrageenan-induced paw edema in rats (ED50 = 20 mg/kg). It also reduces the formation of neocapillaries and decreases microvascular density as well as VEGF, VEGF receptor 2 (VEGFR2), and hypoxia-inducible factor-1α (HIF-1α) expression in a CaSki cervical cancer nude mouse xenograft model when administered at doses of 100, 300, and 500 mg/kg.
Chemical Properties Yellow Solid
Uses Tetrahydro Curcumin is a major metabolite of Curcumin (C838500) that has been shown to have protective effects against diabetes and vascular dysfunction via alleviation of oxidative stress.
Definition ChEBI: A beta-diketone that is curcumin in which both of the double bonds have been reduced to single bonds.
 
Tetrahydrocurcumin Preparation Products And Raw materials
Raw materials Curcumin-->Ferulic Acid-->3,5-Heptanedione, 1,7-bis[4-(acetyloxy)-3-methoxyphenyl]--->3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID-->Vanillin

 

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