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China Biggest Factory & Manufacturer supply G418 Sulfate (Geneticin)
China Biggest Factory & Manufacturer supply G418 Sulfate (Geneticin)
China Biggest Factory & Manufacturer supply G418 Sulfate (Geneticin)
China Biggest Factory & Manufacturer supply G418 Sulfate (Geneticin)
China Biggest Factory & Manufacturer supply G418 Sulfate (Geneticin)

China Biggest Factory & Manufacturer supply G418 Sulfate (Geneticin)

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price:USD 1.0000 -2.0000

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

G418 Sulfate Geneticin 108321-42-2

Quick Details

  • Appearance:white powder
  • Application:chemicals industry
  • PackAge:25KG/Drum
  • ProductionCapacity:5|Metric Ton|Month
  • Storage:2-8°C
  • Transportation:By air /Sea/ coruier

Superiority:

Geneticin Basic information
Product Name: Geneticin
Synonyms: TRYPSIN INHIBITOR SOYBEAN REAGENT GRADE;G-418 disulfate,Geneticin;Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only;Geneticin disulfate saltPotency ≥ 700 ug/mg (anhydrous basis);Antibiotic G418 Geneticin®;2-[4,6-diamino-3-[3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol,sulfuric acid;G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested;D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)
CAS: 108321-42-2
MF: C20H42N4O14S
MW: 594.63
EINECS: 600-864-4
Product Categories: Antibiotic Explorer;antibiotic;Inhibitors
Mol File: 108321-42-2.mol
Geneticin Structure
 
Geneticin Chemical Properties
storage temp.  2-8°C
solubility  H2O: 50 mg/mL
form  white powder
color  white to off-white
optical activity [α]/D (Specific Rotation: +104.4o (c=0.3% in H2O at 26oC))
Water Solubility  soluble
InChIKey QNQZPJLBGRQFDD-ZLRXUJDMSA-N
 
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38-42/43
Safety Statements  22-24/25-36/37-23-36-26-45
WGK Germany  3
RTECS  CB9378500
HS Code  29419090
MSDS Information
 
Geneticin Usage And Synthesis
Chemical Properties white to off-white powder
Uses antibacterial
Uses membrane-permeant allosteric effector of hemoglobin therapeutic in cardiovascular diseases and cancer
Uses Antihypertensive
Uses Plant cell culture, tested
Uses Geneticin Disulfate Salt, is an aminoglycoside antibiotic, structurlly similar to Gentamicin B1. It is produced by Micromonospora rhodorangea. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
General Description

The optimal concentration of G418 for selection of resistance will vary according to the organism and/or cell type under investigation. In general, the concentration of active drug required for selection is as follows: Dictyostelium sp.: 10-100 μg/ml Plant cells: 10-100 μg/ml Yeast cells: 0.5-1.0 μg/ml Mammalian cells: 0.1-2.0 μg/ml

Biochem/physiol Actions Mode of Action: G418 blocks polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes.Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes.
 
Geneticin Preparation Products And Raw materials

 

Details:

 

Geneticin Basic information
Product Name: Geneticin
Synonyms: TRYPSIN INHIBITOR SOYBEAN REAGENT GRADE;G-418 disulfate,Geneticin;Geneticin Disulfate (G418), Antibiotic for Culture Media Use Only;Geneticin disulfate saltPotency ≥ 700 ug/mg (anhydrous basis);Antibiotic G418 Geneticin®;2-[4,6-diamino-3-[3-amino-4,5-dihydroxy-6-(1-hydroxyethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol,sulfuric acid;G 418 Sulfate, Sterile-Filtered Aqueous Solution, Cell Culture Tested;D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:2)
CAS: 108321-42-2
MF: C20H42N4O14S
MW: 594.63
EINECS: 600-864-4
Product Categories: Antibiotic Explorer;antibiotic;Inhibitors
Mol File: 108321-42-2.mol
Geneticin Structure
 
Geneticin Chemical Properties
storage temp.  2-8°C
solubility  H2O: 50 mg/mL
form  white powder
color  white to off-white
optical activity [α]/D (Specific Rotation: +104.4o (c=0.3% in H2O at 26oC))
Water Solubility  soluble
InChIKey QNQZPJLBGRQFDD-ZLRXUJDMSA-N
 
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38-42/43
Safety Statements  22-24/25-36/37-23-36-26-45
WGK Germany  3
RTECS  CB9378500
HS Code  29419090
MSDS Information
 
Geneticin Usage And Synthesis
Chemical Properties white to off-white powder
Uses antibacterial
Uses membrane-permeant allosteric effector of hemoglobin therapeutic in cardiovascular diseases and cancer
Uses Antihypertensive
Uses Plant cell culture, tested
Uses Geneticin Disulfate Salt, is an aminoglycoside antibiotic, structurlly similar to Gentamicin B1. It is produced by Micromonospora rhodorangea. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
General Description

The optimal concentration of G418 for selection of resistance will vary according to the organism and/or cell type under investigation. In general, the concentration of active drug required for selection is as follows: Dictyostelium sp.: 10-100 μg/ml Plant cells: 10-100 μg/ml Yeast cells: 0.5-1.0 μg/ml Mammalian cells: 0.1-2.0 μg/ml

Biochem/physiol Actions Mode of Action: G418 blocks polypeptide synthesis and protein elongation by inhibiting synthesis at the 70S and 80S ribosomes.Antimicrobial Spectrum: G418 selects for cells stably transfected with an iNOS promoter construct and neomycin resistance gene and shows activity against protozoa and helminthes.
 
Geneticin Preparation Products And Raw materials

 

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