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Sodium Deoxycholate Sodium Deoxycholate 302-95-4
Sodium deoxycholate Basic information |
Product Name: | Sodium deoxycholate |
Synonyms: | OXIDE EXTRACT;SODIUM CHOLEATE;Deoxycholic acid, sodium salt, 99%, extra pure;Sodium Deoxycholate [for Electrophoresis];Deoxycholic acid sodium;Sodium deoxycholate ,98%;SodiuM 3,12-dihydroxycholanate;sodium 3-α,12-α-dihydroxy-5-β-cholan-24-oate |
CAS: | 302-95-4 |
MF: | C24H41NaO4 |
MW: | 416.58 |
EINECS: | 206-132-7 |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Bile SaltsDetergents;Anionic;Detergents;Detergents A to Z;Steroids;302-95-4 |
Mol File: | 302-95-4.mol |
Sodium deoxycholate Chemical Properties |
Melting point | 357-365 °C |
alpha | 44 º (c=2, H2O) |
density | 1.012 at 20.07℃ |
vapor pressure | 0Pa at 20℃ |
Fp | >110°C (own results) |
storage temp. | room temp |
solubility | water: soluble1 gm in 10 ml, clear, colorless to very faintly yellow |
form | Powder |
color | Yellow-tan |
PH | 7.5-9.0 (20g/l, H2O, 20℃) |
Odor | Odorless |
PH Range | 7 - 10 |
optical activity | [α]20/D +44±2°, c = 2% in H2O |
Water Solubility | 330 g/L (15 ºC) |
BRN | 3581950 |
LogP | 5.35 at 22℃ and pH5.7 |
Surface tension | 41.8mN/m at 1g/L and 20℃ |
CAS DataBase Reference | 302-95-4(CAS DataBase Reference) |
EPA Substance Registry System | Cholan-24-oic acid, 3,12-dihydroxy-, monosodium salt, (3.alpha.,5.beta.,12.alpha.)- (302-95-4) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 22-37 |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
RTECS | FZ2250000 |
F | 3-10 |
TSCA | Yes |
HS Code | 29181930 |
Toxicity | LD50 orally in Rabbit: 1370 mg/kg |
MSDS Information |
Provider | Language |
---|---|
Sodium deoxycholate | English |
ACROS | English |
SigmaAldrich | English |
Sodium deoxycholate Usage And Synthesis |
Chemical Properties | Sodium deoxycholate is white to cream crystalline powder |
Uses | Sodium deoxycholate is used as a component in cell lysis buffers. |
Uses | Sodium deoxycholate is an ionic detergent for the solubilization of membrane-bound proteins. |
Uses | Sodium deoxycholate is used as a choleretic and an anionic detergent. It is useful for the extraction of membrane receptors, plasma membrane proteins, nuclei isolation and solubilizes fats as well as membrane components. It acts as an intermediate for the production of corticosteroids and microbiological diagnostic media. In addition, it acts as a catalyst in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins. |
General Description | Sodium deoxycholate is a bile salt and an ionic detergent. Bile salts work along with lipids/fats/cholesterol and form mixed micelles in the intestine. These micelles help in fat digestion and absorption through the intestinal wall. |
Biochem/physiol Actions | Solubilizes fats for absorption in the intestines. |
Safety Profile | Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NasO. |
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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation. We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
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