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Agomelatine 138112-76-2 Agomelatine 138112-76-2
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【Product name】Agomelatine
【Synonym】N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamide
【CAS NO.】138112-76-2
【Mol. Formula】C15H17NO2
【Mol. Weight】243.3
【Assay】98.0%~102.0%
【Appearance】Off-white or white crystalline powder; odourless
【Standard】Medical grade
【Packing】25kgs/drum (standard packing)
【Storage】Tight container, protect from light
Agomelatine is one kind of off-white or white crystalline powder, odourless. It is the world's first melatonin receptor, MT1 and MT2 agonist antidepressants, suitable for the treatment of major depressive episodes in adults. Agomelatine another unique target action is in the melatonin receptor.Through agonism on the MT1MT2 receptor, Agomelatine has well improved sleep quality while improving their daytime arousal state.
Quality Standard
Items |
Specification |
|
Assay (HPLC) |
98.0%~102.0% |
|
Appearance |
Off-white or white crystalline powder; odourless |
|
Solubility |
Easily dissolved in ethanol or acetone, slightly soluble in water |
|
Absorption |
On 243nm, the wavelength at 221~235 |
|
Identify |
Chromogenic reaction |
Positive |
|
Ultraviolet Absorbance |
The max absorption at the wavelength of 243~298nm The min absorption at the wavelength of 229nm |
|
Melting point |
108℃~110℃ |
Loss on drying |
≤1.0% |
|
Residue on ignition |
≤0.10% |
|
Heavy metal |
<10 ppm |
|
Maximum single impurity |
≤0.10% |
|
Total impurity |
≤0.50% |
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