- Min.Order :1 Kilogram
- Purity: USP/EP/BP
- Payment Terms : L/C,T/T,Other
Keywords
Bicalutamide tamide 90357-06-5
Quick Details
- Appearance:White crystallization
- Application:Reaction properties,Immunosuppressive effect,anti- Virus response
- PackAge:1kg/tin
- ProductionCapacity:1.5|Metric Ton|Day
- Storage:room temperature
- Transportation:AIR SEA TRAIN
Superiority:
We are very compeitive on Bicalutamide.Our mfr with DMF document.
| Product Name: | Bicalutamide |
| CAS: | 90357-06-5 |
| MF: | C18H14F4N2O4S |
| MW: | 430.37 |
| EINECS: | 200-001-8 |
| Product Categories: | MODRASTANE;API;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Active Pharmaceutical Ingredients;Antiandrogen;Antineoplastic (Hormonal);anti-neoplastic;API's |
| Mol File: | 90357-06-5.mol |
Details:
| Description | Bicalutamide was launched in the United Kingdom, its first worldwide market, for the treatment of advanced prostate cancer in combination with an LHRH analog or surgical castration. A non-steroidal, peripherally selective antiandrogen, bicalutamide inhibits the action of dihydrotestosterone and testosterone at target sites by competitive binding to the cytosolic androgen receptor. It was reportedly well tolerated with no significant cardiovascular and metabolic side effects due to the benefit of lacking any steroid activity. The efficacy of bicalutamide as a monotherapy has been demonstrated clinically. Promising response rates were also reported in treating colorectal, breast, pancreas and non-small cell lung cancers. |
| Chemical Properties | Off-White Crystalline Solid |
| Uses | adrenocortical suppressant, antineoplastic, steroid biosynthesis inhibitor |
| Uses | Non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal) |
| Uses | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Uses | Bicalutamide (CDX) has been used as an androgen receptor (AR) antagonist in prostate, bladder cancer cell lines and human fetal skeletal muscle cells. It has also been used as a supplement in RPMI 1640 for culturing androgen-independent LNCaP (LNCaP-AI) cell line. |
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