- Min.Order :1 Kilogram
- Purity: USP/EP/BP
- Payment Terms : L/C,T/T,Other
Keywords
Tenofovir Alafenamide Fumarate TAF 379270-37-8
Quick Details
- Appearance:White crystallization
- Application:Anti- Virus response
- PackAge:1kg/tin
- ProductionCapacity:1|Metric Ton|Day
- Storage:
- Transportation:AIR SEA TRAIN
Superiority:
We are very compeitive on Tenofovir Alafenamide Fumarate.Our mfr is WC certified for this item with DMF document.
| Product Name: | Tenofovir Alafenamide |
| CAS: | 379270-37-8 |
| MF: | C21H29N6O5P |
| MW: | 476.47 |
| EINECS: | 1592732-453-0 |
| Product Categories: | Inhibitors;Intermediate |
| Mol File: | 379270-37-8.mol |
Details:
| Description | Tenofovir Alafenamide (GS-7340) is a prodrug of tenofovir, which is a reverse transcriptase inhibitor, used to treat HIV and Hepatitis B.-Reverse Transcriptase inhibitor. It was developed by Gilead Sciences. Compared to tenofovir disoproxil fumarate, tenofovir alafenamide has a greater antiviral activity and better distribution into lymphoid tissues. |
| Description | Tenofovir alafenamide fumarate is an oral phosphonoamidate prodrug of the reverse transcriptase inhibitor tenofovir. It was approved by the USFDA for the treatment of chronic hepatitis B virus infection with compensated liver disease. Tenofovir alafenamide fumarate was discovered and developed by Gilead as a potentially safer form of the previously approved tenofovir disoproxil fumarate (Viread). |
| Definition | ChEBI: An L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)( henoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection. |
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