ODM-201 1297538-32-9 cas 1297538-32-9
Classification: Pharmaceutical
Cas NO.: 1297538-32-9
Name: ODM-201
Molecular Formula: C19H19ClN6O2
Boiling Point: 719.5±60.0
Refractive index:1.681
Flash Point: 388.9±32.9 °C
Purity: 99%
usage: R&D, intermediates.
Brand Name: Darolutamide
EINECS: 829-313-8
Aliase: Darolutamide
Purity: 99%
Appearance:a white or almost white crystalline powder
Brand: Darolutamide
Package: 25kg drum
ODM-201 is a novel androgen receptor (AR) inhibit designed to inhibit the growth of prostate cancer cells through binding to the AR to inhibit the testosterone-induced AR nuclear translocation. It is particularly used in patients with progressive metastatic castration-resistant prostate cancer. It is effective in inhibiting the activity of some mutant ARs emerging during antiandrogen therapies, including the F876L mutation version which is resistant to enzalutamide and ARN-509 (the second-generation antiandrogens).Therefore, it has potential to overcome the resistance issue occurring upon AR-targeted therapies.
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