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factory supply GMP,DMF,CEP Metamizole
factory supply GMP,DMF,CEP Metamizole
factory supply GMP,DMF,CEP Metamizole
factory supply GMP,DMF,CEP Metamizole

factory supply GMP,DMF,CEP Metamizole

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: USP/EP/BP
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Keywords

Metamizole sodium Metamizole 68-89-3

Quick Details

  • Appearance:White crystallization
  • Application:Cardiovascular APIs,Sartan antihypertensive drugs
  • PackAge:25kg/drum
  • ProductionCapacity:10|Metric Ton|Day
  • Storage:room temperature
  • Transportation:AIR SEA TRAIN

Superiority:

We are very compeitive on Metamizole sodium.Our mfr is GMP certified for this item with CEP document. 

Product Name: Metamizole sodium
CAS: 68-89-3
MF: C13H16N3NaO4S
MW: 333.34
EINECS: 200-694-7
Product Categories: Aromatics;Heterocycles;DIO - DIZForensic and Veterinary Standards;Cosmetic Ingredients & Chemicals;Intermediates & Fine Chemicals;Sulfur & Selenium Compounds;PHARMACEUTICALS;Alphabetic;D;Drugs&Metabolites;Neat Compounds
Mol File: 68-89-3.mol
Metamizole sodium Structure

Details:

Metamizole sodium Usage And Synthesis
Description Dipyrone is a water soluble pyrazolone derivative available in oral, rectal and injectable forms. It has analgesic, antipyretic, antispasmodic, and anti-inflammatory properties. Dipyrone is used most commonly to treat severe pain, particularly, for pain associated with smooth muscle spasm or colic affecting the gastrointestinal, biliary or urinary tracts. It is useful for fever that is refractory to other treatment. Because of the risk of serious adverse effects, such as agranulocytosis, its use is justified only in serious situations where no alternative is available or suitable.
Drug Instructions Alias: dipyrone, NOVALGIN; Noramidopyrine, Metamizole sodium,metamizole
Property: This product is white or yellow-white crystal or crystalline powder, odorless, slightly bitter taste, soluble in water.
Action: Dipyrone is the derivative of aminopyrine, its has a significant effect of antipyretic analgesia. The antipyretic effect of it is three times as aminopyrine, the analgesic effect is similar to that of aminopyrine.
Process vivo: Easily absorbed orally, mainly metabolized by the liver and excreted of renal
Indications: It is mainly used for cooling, acute arthritis, headache, rheumatic neuralgia, toothache and muscle pain etc.

Dosage
Oral or intranasal administration. For oral, the adult should take 0.5g of the medicine and three times a day, the amount of the child is 8-10mg/ kg, the number of the times is according to the necessary. For intranasal, the child under 5 years old can take 1-2drops for each nostril, can take the medicine another time if necessary,for the patient above 5 years old increase the dosage appropriately.
Note
1, The dosage should be controled strictly to prevent collapse.
2, The intramuscular injection can cause atrophy and erosion to the local muscle, it is abandoned now.
3, The patient who has a allergy to the praziquantel can not use the dipyrone
4, It not suitable for a long-term application, Please pay attention to the granulocytes.

Specification
Tablets:each table is weight for 0.25g or 0.5g; Injection: each ingection has the specification of 0.25g/1ml or 0.5g/2ml; Drops: solution with the concentration of 10%~20%
Side effects of dipyrone 1, The side effects contain the allergies, exhaustion, leukopenia, thrombocytopenia even the severe aplastic anemia.
2, Some people may also suffering the nephrotoxicity and gastrointestinal bleeding after they take the dipyrone.The most serious side effect is lethal agranulocytosis.
Uses It has the effect of detoxification, analgesic and anti-rheumatic etc and mainly used for cooling, but also can be applied to cure the acute arthritis, rheumatic pain, muscle pain and headache etc.
 

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