factory supply GMP,...

factory supply GMP,DMF Tiapride hydrochloride
factory supply GMP,DMF Tiapride hydrochloride
factory supply GMP,DMF Tiapride hydrochloride
factory supply GMP,DMF Tiapride hydrochloride

factory supply GMP,DMF Tiapride hydrochloride

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: USP/EP/BP
  • Payment Terms : L/C,T/T,Other

Keywords

Tiapride HCL Tiapride 51012-32-9

Quick Details

  • Appearance:White crystallization
  • Application:Antiemetic
  • PackAge:25kg/drum
  • ProductionCapacity:10|Metric Ton|Day
  • Storage:room temperature
  • Transportation:AIR SEA TRAIN

Superiority:

We are very compeitive on Tiapride HCL.Our mfr is GMP certified for this item with DMF document. 

Product Name: Tiapride
Synonyms: TIAPRIDE;Tiapride hcl;N-[2-Diethylamino ethyl]-5-[methylsufonyl]-o-anisamide;Cyclovirobune D;N-(2-Diethylaminoethyl)-2-methoxy-5-methylsulfonylbenzamide;N-[2-(Ethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)benzamide;N-[2-(Diethylamino)ethyl]-5-(methylsulfonyl)-2-methoxybenzamide;N-[2-(Diethylamino)ethyl]-5-mesyl-2-methoxybenzamide
CAS: 51012-32-9
MF: C15H24N2O4S
MW: 328.43
EINECS: 256-907-9
Product Categories: Dopamine receptor;NATURETIN;Active Pharmaceutical Ingredients
Mol File: 51012-32-9.mol
Tiapride Structure

Details:

Tiapride Usage And Synthesis
Originator Tiapridal,Delagrange,France,1977
Uses diuretic, antihypertensive
Uses Tiapride hydrochloride is a D2DR and D3DR inhibitor; Anti-psychotic agent and alternative treatment for Tourette’s syndrome.
Manufacturing Process 5 g of 2-methoxy-5-methylsulfonylbenzoic acid, 50 ml of dioxan, 3.02 ml of triethylamine and 3 g of isobutyl chloroformate were introduced into a 250 ml balloon flask at ambient temperature.
After the mixture had been stirred for 30 minutes, 3 g of N,N_x0002_diethylethylenediamine were added. The reaction mixture was stirred for 6 hours and the solvents were evaporated under vacuum.
The residue was dissolved in 50 ml of water and the solution was made alkaline with sodium hydroxide. The precipitate formed was filtered, washed and dried in a drying oven at 60°C. 6 g of N-(diethylaminoethyl)-2-methoxy- 5-methylsulfonylbenzamide (melting point: 124°C to 125°C) was produced.
 

 

 

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