99% up by HPLC PARE...

99% up by HPLC PARECOXIB SODIUM 198470-85-8

99% up by HPLC PARECOXIB SODIUM 198470-85-8

Min.Order / FOB Price:Get Latest Price

25 Kilogram

Negotiable

  • Min.Order :25 Kilogram
  • Purity: 99% up by HPLC
  • Payment Terms : L/C,D/A,D/P,T/T

Keywords

PARECOXIB SODIUM PARECOXIB 198470-85-8

Quick Details

  • Appearance:White powder
  • Application:API
  • PackAge:25kg/drum
  • ProductionCapacity:10|Metric Ton|Month
  • Storage:Normal templeture
  • Transportation:normal

Superiority:

Why is SINOWAY:
1) Specialized in pharmaceutical and healthcare industrial since 1987
2) ISO 9001:2015 & SGS audited supplier .
3) Accept various payment terms : T.T 30-60 days.
4) We have warehouse in USA with quickly shipment .
5) We can do different terms of FOB ,CIF/CIP ,DDP ...

Details:

Product name

Parecoxib Sodium

CAS No.

198470-85-8

Molecular Formula

C19H18N2O4S. Na

Molecular Weight

392.404

Molecular Structure

Quality Standard

98.0% up by HPLC

Appearance

White to almost white crystalline powder

 

 

 

ANALYSIS

SPECIFICATION

RESULTS

Appearance

White to almost white crystalline powder

Conform

Identification

A: The retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution.

Conform

B: Comparing with the spectrum obstained with CRS

Conform

C: Reaction of sodium

Conform

Clarity and color solution

Meets the requirements

Conform

pH

7.5-9.0

8.3

Chlorides

≤ 0.02%

< 0.02%

Ammonium

≤ 0.02%

< 0.02%

Sulfate

≤ 0.02%

< 0.02%

Water

≤ 2.0%

0.4%

Heavy metals

≤ 0.002%

< 0.002%

Propionic acid

≤ 0.15%

Not detected

Related substance

Impurity I ≤ 0.15%

Not detected

Impurity II ≤ 0.15%

Not detected

Impurity III ≤ 0.15%

Not detected

Impurity IV ≤ 0.15%

Not detected

Impurity V ≤ 0.15%

Not detected

Impurity VI ≤ 0.15%

Not detected

Other single impurity ≤ 0.10%

Not detected

Total impurities ≤ 0.50%

Not detected

Residual solvent

Ethanol ≤ 5000ppm

45.3ppm

 

Acetone ≤ 5000ppm

317.5ppm

 

Dichloromethane ≤ 600ppm

Not detected

 

Ethyl acetate ≤ 5000ppm

59.6ppm

 

Triethylamine ≤ 320ppm

1.0ppm

 

Toluene ≤ 890ppm

7.7ppm

Endotoxin

≤ 2.9EU/mg

< 2.9EU/mg

Microbial limit

TAMC ≤ 100cfu/g

< 1cfu/g

TYMC ≤ 10cfu/g

< 10cfu/g

E.Coli: Not detected

Not detected

Assay

(anhydrous substance)

98.0%-102.0%

100.8%

Conclusion

The product meets the specification

 

 

 

What is Parecoxib Sodium 


Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo.

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