2-Amino-5-bromobenz...

2-Amino-5-bromobenzoic acid
2-Amino-5-bromobenzoic acid
2-Amino-5-bromobenzoic acid
2-Amino-5-bromobenzoic acid
2-Amino-5-bromobenzoic acid

2-Amino-5-bromobenzoic acid

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1 Kilogram

FOB Price:USD 15.0000 -50.0000
  • Min.Order :1 Kilogram
  • Purity: 97%
  • Payment Terms : T/T

Keywords

2-Amino-5-bromobenzoic acid,97% 2 - aMino - 5 - broMine benzoic acid Anthranilic acid, 5-bromo-

Quick Details

  • Appearance:Beige powder
  • Application:It is used in the preparation of hepatitis C virus NS5b RNA polymerase inhibitors. Also used in the determination of cobalt, copper, nickel, and zinc.
  • PackAge:bottle/drum
  • ProductionCapacity:1000000|Kilogram|Month
  • Storage:cool and dry
  • Transportation:by air orby sea or by express

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Details:

CAS: 5794-88-7
MF: C7H6BrNO2
MW: 216.03
EINECS: 227-338-3
Product Categories: Anilines, Amides & Amines;Bromine Compounds;Carboxylic Acids;Phenyls & Phenyl-Het;Benzoic acid series;Four-membered heterocyclic compound,Others;FINE Chemical & INTERMEDIATES;Amino Acids and Derivatives;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Carboxylic Acids;Phenyls & Phenyl-Het;Benzoic acid;Organic acids;Acids & Esters;bc0001
Mol File: 5794-88-7.mol
2-Amino-5-bromobenzoic acid Structure
 
2-Amino-5-bromobenzoic acid Chemical Properties
Melting point  213-215 °C (lit.)
Boiling point  265.51°C (rough estimate)
density  1.6841 (rough estimate)
refractive index  1.6120 (estimate)
storage temp.  Keep in dark place,Inert atmosphere,Room temperature
solubility  Soluble in methanol and dimethyl sulfoxide.
form  Powder
pka 4.55±0.10(Predicted)
color  Beige
Sensitive  Light Sensitive
Merck  14,1405
BRN  639028
CAS DataBase Reference 5794-88-7(CAS DataBase Reference)
NIST Chemistry Reference 2-Amino-5-bromobenzoic acid(5794-88-7)
2-Amino-5-bromobenzoic acid Usage And Synthesis
Synthesis A solution of bromine (7.2 g, 2 mL, 40 mmol) in 47 mL glacial acetic acid was added dropwise to sodium 2-aminobenzoate (6.4 g, 40 mmol) in 32 mL of glacial acetic acid at 15 °С and the mixture was stirred for 1 h at the same temperature. The product was filtered off, washed with benzene and dried in the dark. The bromobenzoic acids containing mixture (0.5 g) was added to 10 mL of boiling water followed by the addition of 1.3 mL of concentrated hydrochloric acid and hot filtration under vacuum. The insoluble material contained 2-amino-3,5-dibromobenzoic acid, whereas 2- amino-5-bromobenzoic acid precipitated upon cooling of the filtrate. IR (suspension in nujol, cm−1 ): 3497, 3383,  1675, 1616, 1587, 1548, 1423, 1377, 1316, 1292, 1239, 1160, 1127, 812, 748, 691.
Chemical Properties slight yellow to white powder
Uses 2-Amino-5-bromobenzoic acid is a brominated derivative of Antharilinic Acid (A679222). 2-Amino-5-bromobenzoic acid displays plant growth-regulator activity. 2-Amino-5-bromobenzoic acid is used in the preparation of hepatitis C virus NS5b RNA polymerase inhibitors.

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