CasNo.2398-96-1,High quality of Tolnaftate,(2398-96-1) Suppliers

1 Kilogram	FOB Price: USD 25.0000

Min.Order :1 Kilogram
Purity: 99%
Payment Terms : L/C,T/T,MoneyGram

Keywords

2-naphthyl n-methyl-n-(3-tolyl)thionocarbamate Aftate Carbanilic acid, m,N-dimethylthio-, O-2-naphthyl ester

Quick Details

Appearance:white to off-white powder
Application:Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections su
PackAge:carton boc
ProductionCapacity:1000000|Kilogram|Month
Storage:cool and dry
Transportation:by air or by sea or by express

Superiority:

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in lead acetate, diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

1. Rich experience.Having been specialized in this field for years, we have rich experience and widespread sales network around the word. Our hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. We are not got good feedback from our guest, but also established long business relationship with them.

2. Great quality and high purity.Good quality is one secret for our success. All of our products enjoys high purity. Thus, it can make sure our client's need. Welcome order the samples, MOQ just 10 grams.

3. Safest and fastest delivery.We have mass stock, so that we can arrange the delivery within 24hours once receiving the payment. Tracking number would be informed quickly after shipment. We have our own way of packing which could ship 0.01 kilo to 50 kilo products a time.

4. Good after-sales service.24/7 is available. We will tell you the package updated info ASAP. And try our best to solve various problems customers encountered!

5. Experiential shopping

Our Advantages
1.Own chemical factory

2.Abundant professional production experience

3.Sample is free of charge and in stock with fast delivery

4. Price,quality & service, we care that all you cares

5. Prompt reply keep in touch to save your times

6.Easily customs clearance, we're very good to all these controls

7.Dedicated researchers to make your customization.

Details:

Product details

CAS:	2398-96-1
MF:	C19H17NOS
MW:	307.41
EINECS:	219-266-6
Product Categories:	Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;TINACTIN
Mol File:	2398-96-1.mol

Tolnaftate Chemical Properties

Melting point	110.5-111.5°C
Boiling point	453.4±38.0 °C(Predicted)
density	1.1328 (rough estimate)
refractive index	1.6970 (estimate)
storage temp.	Sealed in dry,2-8°C
solubility	Soluble in chloroform at 50 mg/ml. Sparingly soluble in ethanol or methanol
pka	-0.35±0.50(Predicted)
form	powder
color	white to off-white
Water Solubility	<0.1 g/100 mL at 22 ºC
λmax	258nm(MeOH)(lit.)
Merck	14,9519
InChIKey	FUSNMLFNXJSCDI-UHFFFAOYSA-N
LogP	5.142 (est)
NIST Chemistry Reference	Tolnaftate(2398-96-1)
EPA Substance Registry System	Tolnaftate (2398-96-1)

Tolnaftate Usage And Synthesis

Description	Tolnaftate is a thiocarbamate antifungal agent. It is active against clinical isolates of the dermatophytes T. rubrum, T. mentagraphytes, T. verrucosum, E. floccosum, and M. canis (MIC₅₀s = 50, 100, 6, 50, and 50 ng/ml, respectively), as well as 18 additional yeast and filamentous fungi species (MIC = 0.003-0.8 μg/ml)., Tolnaftate also reduces aflatoxin production in A. parasiticus in a concentration-dependent manner. It inhibits squalene epoxidase with an IC₅₀ value of 12.5 μg/ml in a cell-free assay.
Chemical Properties	White Solid
Originator	Tinactin,Schering,US,1965
Uses	Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athlete s foot, jock itch, and ringworm1. It also has been used as a comparator compound for antifungal efficiency studies.
Uses	antifungal for cutaneous infections. Tolnaftate (Aftate, Tinactin, etc.) is an odorless and nonstaining synthetic antifungal agent whose exact mechanism of action is unknown. It is effective against dermatophytes and P. orbiculare and Pityrosporum ovale. It is ineffective against C. albicans and bacteria.
Uses	Tolnaftate topical is used to treat skin infections such as athlete's foot, jock itch, and ringworm infections. Tolnaftate is also used, along with other antifungals, to treat infections of the nails, scalp, palms, and soles of the feet.
Definition	ChEBI: A monothiocarbamic ester that is the methyl(3-tolyl)carbamothioate ester of 2-naphthol. A synthetic anti-fungal agent used to treat jock itch, athlete's foot and ringworm.
Indications	Tolnaftate (Aftate, Tinactin, etc.) is an odorless and nonstaining synthetic antifungal agent whose exact mechanism of action is unknown. It is effective against dermatophytes and P. orbiculare and Pityrosporum ovale. It is ineffective against C. albicans and bacteria.

Product usage

Tolnaftate topical is used to treat skin infections such as athlete's foot, jock itch, and ringworm infections. Tolnaftate is also used, along with other antifungals, to treat infections of the nails, scalp, palms, and soles of the feet.

Company profile

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in lead acetate, diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterprises.Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.