Natural Ingredients Manufacturer Directly Offer ≥99% Protocatechuic Acid 3,4-Dihydroxybenzoic Acid Can be Used as Pharmaceutical Intermediate

Details:

Natural Ingredients Manufacturer Directly Offer ≥99% Protocatechuic Acid 3,4-Dihydroxybenzoic Acid Can be Used as Pharmaceutical Intermediate 

Product Description: 

Protocatechuic acid, also known as 3,4- dihydroxybenzoic acid, is a type of phenolic acid and serves as a precursor for the synthesis of various complex molecules, such as cyanidin 3-O-β-D-glucoside found in plants. It is one of several isomers of dihydroxybenzoic acid. Protocatechuic acid is a primary metabolite of antioxidant polyphenols in green tea and exhibits some inhibitory effects on tumor cells. Protocatechuic acid is widely present in common medicinal herbs like Eleutherococcus senticosus, rehmannia, and Rhododendron molle. It possesses pharmacological activities, including antiplatelet aggregation, reducing myocardial oxygen consumption, enhancing myocardial tolerance to oxygen, slowing heart rate, antimicrobial properties, and analgesic effects. Moreover, protocatechuic acid exhibits antioxidant, anti-tumor, and neuroprotective properties. Using protocatechuic acid as a raw material, drugs like resveratrol, meclofenamic acid hydrochloride, berberine hydrochloride II, and itopride hydrochloride can be synthesized. Combining protocatechuic acid acid with other substances in pharmaceutical formulations can effectively reduce the time required for wound healing in diabetic foot ulcers.

Test Report of Natural Purity: Purity Natural >96%

Product efficacies：

1. Anti-Cancer: Protocatechuic acid is used as a raw material to synthesize the anticancer drug Erlotinib through various reactions such as etherification and nitration.
2. Antibacterial: Protocatechuic acid has inhibitory effects on various bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae, Haemophilus influenzae, Pseudomonas aeruginosa, Escherichia coli, and Proteus vulgaris. In mice, it reduces the mortality rate caused by Staphylococcus aureus infection by 30%.
3. Expectorant and Bronchodilator: Protocatechuic acid has shown significant bronchodilatory effects in a guinea pig histamine aerosol-induced asthma test. It is clinically used to treat chronic bronchitis. In mice administered 4.68 mg of Protocatechuic acid by gastric lavage, it exhibits expectorant effects.
4. Detoxification: Protocatechuic acid has a protective effect against cobra venom poisoning in mice. It also has a significant inhibitory effect on "formalin-induced foot swelling" in mice, which is stronger than salicylic acid and close to acetylsalicylic acid.
5. Animal Feed Additive:(1) Adding Protocatechuic acid to animal feed formulas enhances the antioxidant and anti-inflammatory abilities of weaning piglets, alleviating oxidative damage caused by weaning and effectively reducing inflammatory responses and improving anemia, thus lowering piglet mortality. Protocatechuic acid can substitute antibiotics to alleviate stress-induced ailments in weaning piglets.(2) The use of a feed additive containing 0.75-3% Protocatechuic acid improves boar's spermatogenic ability, enhances sperm quality, and extends their reproductive lifespan.(3) When used in the feed of crucian carp, in conjunction with Puerarin and combined with vitamins, minerals, and heat-resistant probiotics, Protocatechuic acid improves lipid metabolism and has a significant anti-inflammatory and detoxifying effect on hepatitis and enteritis, reinforcing the overall immune system and metabolic balance of crucian carp. This results in higher weight gain, thicker dorsal muscle, and better coloration.(4) Properly dosed Protocatechuic acid in feed significantly improves the growth performance and meat quality of yellow feather broilers, enhances antioxidant capacity, improves intestinal immune function, and tightens the gut connection. It can also promote gut health by improving the gut microbiome structure, leading to better post-molt layer performance and egg quality. (5) The use of Protocatechuic acid in feed additives for ducks increases their weight by 20-25%, and the nutritional content becomes richer. (6) Silkworms exposed to organic nitrogen pesticides exhibit signs of excitement, reduced mulberry leaf consumption, and flat or erratic silk spinning. After poisoning, spraying tyrosine solution on the silkworm surface and feeding them non-toxic mulberry leaves sprayed with Protocatechuic acid can reduce the silkworm death rate from 100% (feeding non-toxic mulberry leaves only) to 0%.
6. Alternative to Bisphenol A (BPA) in New Materials: Protocatechuic acid contains hydroxyl and carboxyl functional groups that can introduce flexible segments, leading to a higher cross-linking density, improved heat stability, impact resistance, and greater elongation at break in materials, making it suitable for aerospace applications. Protocatechuic acid-modified acrylic ester resins outperform poly (methyl methacrylate) (PMMA) materials based on bisphenol A in terms of performance.
7. As a Key Ingredient for Synthesizing Vanillin (also known as Vanilla Aldehyde, with the chemical name 3-methoxy-4-hydroxybenzaldehyde): Protocatechuic acid is a primary component used in the synthesis of vanillin, a popular flavor compound used in various food and fragrance products.

Company Profile:

As an innovative bioengineering manufacturer, Vertexyn Bioworks is dedicated to the long-term development of bio-based products. Our products encompass a variety of natural substances that find widespread applications across numerous fields, including pharmaceutical raw materials, intermediates, personal care, functional foods, and animal and plant nutrition.

Vertexyn Bioworks has established a comprehensive technological framework that includes rational design and construction of microorganisms, iterative scaling of fermentation and downstream processing, and product application development.

Vertexyn Bioworks has built a stable production capacity at scale. The total construction area of the factory is 1,5000 m², the annul output of the production line is 300 tons. Committed to utilizing renewable natural sources, Vertexyn Bioworks aims to provide globally valued natural products to customers at low costs and high quality, thereby contributing significantly to the well-being of humanity.

Certifications:

Packaging & Shipping:

FAQ:

1. Can I get some samples before bulk order
Yes, we can supply the free sample, but the shipping cost should be paid by customers.
2. What's your MOQ
Our MOQ starts from 10 gram and other products generally starts from 1 kilogram, for more details you can feel free to contact with us directly. 
3. Is there a discount
Yes, for larger quantity, we always support with better price.

4. How to confirm the Product Quality before placing orders

You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.

5. How to start orders or make payments

You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.

6. How to contact us
You can chat with us by Trademanager,WhatsApp&Skype Online. You can dial our telephone directly or send E-mail to us and you will get our reply.