factory supply GMP,DMF Sacubitril + Valsartan 936623-90-4

factory supply GMP,DMF Sacubitril + Valsartan 936623-90-4

Min.Order / FOB Price:Get Latest Price

1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: USP/EP/BP
Payment Terms : L/C,T/T,Other

Keywords

Sacubitril Valsartan 936623-90-4

Quick Details

Appearance:White crystallization
Application:Cardiovascular APIs,Sartan antihypertensive drugs
PackAge:25kg/drum
ProductionCapacity:10|Metric Ton|Day
Storage:room temperature
Transportation:AIR SEA TRAIN

Superiority:

We are very compeitive on LCZ696 Sacubitril + Valsartan.Our mfr is GMP certified for this item with CEP document.

Product Name:	LCZ696
Synonyms:	Entresto;LZC696;[(C24H29N5O3).(C24H29NO5).2.5(H2O).3Na];LCZ696 ENTRESTO TM;LCZ696 Entresto;4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate;Sacubitril mixture with Valsartan;Cocrystal of Sacubitril and Valsartan
CAS:	936623-90-4
MF:	C48H58N6O8
MW:	847.03
EINECS:	000-000-0
Product Categories:	Cardiovascular Series;Inhibitors;API;936623-90-4
Mol File:	936623-90-4.mol

Details:

Losartan potassium Chemical Properties

Melting point	263-265°C
storage temp.	Inert atmosphere,Room Temperature
solubility	Freely soluble in water and in methanol, slightly soluble in acetonitrile.
form	powder or crystals
Merck	14,5583
BRN	5845770
CAS DataBase Reference	124750-99-8(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36/37/39
WGK Germany	3
RTECS	NI6755100
HS Code	2933290000

Losartan potassium Usage And Synthesis

Description

As a angiotensin II receptor antagonist, Losartan Potassium is the potassium salt of losartan with antihypertensive activity, which is mainly used in the therapy of high blood pressure (hypertension) and diabetic nephropathy. It functions by relaxing blood vessels so that blood can flow more easily. It is also effective to help protect the kidneys from damage caused by diabetes and lower the risks of stroke in patients suffering from hypertension and myocardial enlargement. Besides, recent study has suggested that losartan is beneficial to reverse age related dysfunction in maintaining normal blood pressure and cellular energy usage on mitochondria and it can probably be used to treat left ventricular hypertrophy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.