Atracurium Besylate CAS:64228-81-5 USP standard Atracurium Besylate High quality Atracurium Besylate powder
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ITEMS |
SPECIFICATION |
RESULT |
Appearance: |
white or almost white powder, slightly hygroscopic, ordorless |
Confirms |
Very solutable in acetonitrile or chloroform, Soluble in Water, very soluble and practically insolutable in ethyl ether |
Confirms |
|
Identification |
(1) IR |
Conforms |
(2) HPLC |
Conforms |
|
Water |
≤ 5.0% |
0.6% |
Residue on ignition |
≤ 0.2% |
0.1% |
Methyl benzenesulfonate |
≤ 0.1% |
Undetected |
Toluene |
≤ 890ppm (ICH) |
102ppm |
Chromatographic purity |
(1) Laudanosine: ≤ 0.5% (2) Other individual impurities: ≤ 1.0% (3) Total Impurities: ≤ 3.5% |
0.01% 0.38% 1.3% |
Isomer Ratio |
Trans-Trans Isomer: 5%-6.5% |
5.7% |
|
Cis-Trans Isomer: 34.5%-38.5% |
36% |
|
Cis-Cis Isomer: 55%-60% |
58.2% |
Assay |
96%-102% (C65H82N2O18S2 on anhydrous basis) |
100.2% |
Residue Solvents |
(1) Dichloromethane: ≤ 600ppm (2) Acctonitrile: ≤ 410ppm (3) Ethyl ether: ≤ 5000ppm |
Undetected Undetected 1739ppm |
Result |
Confirms to USP34 |
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