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NSI-189 1270138-40-3 NSI-189, >=98%
NSI-189 is an investigational drug being developed by Neuralstem Inc., a biopharmaceutical company.
NSI-189 is a small molecule in clinical development for major depressive disorder (MDD) and in preclinical development for Angelman syndrome, irradiation-induced cognitive impairment, Type 1 and Type 2 diabetes, and stroke.
NSI-189 was studied in phase I and II clinical trials for the treatment of major depressive disorder. As of July 2017, NSI-189 has failed to meet effectiveness outcomes for depression in phase II trials.
Product details
CAS: | 1270138-40-3 |
MF: | C22H30N4O |
MW: | 366.5 |
EINECS: | 1592732-453-0 |
Product Categories: | Inhibitors;API |
Mol File: | 1270138-40-3.mol |
NSI-189 Chemical Properties |
Boiling point | 534.7±50.0 °C(Predicted) |
density | 1.134±0.06 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | Soluble in DMSO |
pka | 6.18±0.10(Predicted) |
form | A crystalline solid |
λmax | 254 nm |
InChI | InChI=1S/C22H30N4O/c1-18(2)10-12-24-21-20(9-6-11-23-21)22(27)26-15-13-25(14-16-26)17-19-7-4-3-5-8-19/h3-9,11,18H,10,12-17H2,1-2H3,(H,23,24) |
InChIKey | DYTOQURYRYYNOR-UHFFFAOYSA-N |
SMILES | C(C1=CC=CN=C1NCCC(C)C)(N1CCN(CC2=CC=CC=C2)CC1)=O |
Company Profile
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