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IDRA 21 22503-72-6 IDRA 21 98%
IDRA-21 is a benzothiadiazine derivative and a positive allosteric modulator of glutamate AMPA receptors (1,2,3,4).
It is able to increase excitatory synaptic strength by inhibiting AMPA receptor desensitization.
IDRA 21 may exhibit therapeutic effects to ameliorate memory deficits in patients with cognitive impairments such as Alzheimer''s disease.
Product details
CAS: | 22503-72-6 |
MF: | C8H9ClN2O2S |
MW: | 232.69 |
EINECS: | 1592732-453-0 |
Product Categories: | API |
Mol File: | 22503-72-6.mol |
IDRA 21 Chemical Properties |
Melting point | 209 °C(Solv: acetic acid (64-19-7)) |
Boiling point | 405.1±55.0 °C(Predicted) |
density | 1.394±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO (Slightly), Methanol (Slightly, Sonicated) |
form | Solid |
pka | 9.78±0.40(Predicted) |
color | Off-White to Pale Yellow |
InChIKey | VZRNTCHTJRLTMU-UHFFFAOYSA-N |
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