4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile

Details:

About:

Lipiavirin is a non-nucleoside reverse transcriptase inhibitor that is commonly used in combination with other antiretroviral drugs to treat human immunodeficiency virus (HIV) infection. Use of ripiverin may cause a transient increase in serum aminotransferase in a few patients, and clinically significant acute liver injury may occur in few patients.

In vitro studies:

Rilpivirine exhibits antiviral activity against wild-type and selective locus single and dual HIV-1 mutants with EC50 ranging from 0.1nM to 2nM. Rilpivirine inhibits viral replication, and first-generation NNRTIs cannot inhibit the concentration of replication and produce a high genetic barrier to hinder development.

In vivo studies:

After intravenous administration of Rilpivirine, the elimination half-life ranges from 4.4 hours in rats to 31 hours in dogs. When administered orally, Rilpivirine's PEG 400 has a half-life range of 2.8 hours in rats and 39 hours in dogs.

Melting Point	245℃
Boiling Point	634.1±65.0 °C
Density	1.27
Storage Condition	Refrigerator
Solubility	Acetone (minimal solution), Chloroform (minimal solution), DMSO (minimal solution), water (minimal solution)
pKa	4.56±0.10

Our advantages:

1) Timely communication, reply within 12 hours.You can leave any messages on our whatsapp or send email to us.

2)Selecting raw materials strictly,our products are the highest purity.

3)Reasonable and competitive price.

4) Free sample for your evaluation.Customers only need to undertake the shipping fee for delivery the samples to your destionation.

5)OEM/ODM Available.Trial order is available for testing after samples.

6) Packaging can be customized according to each buyers' special request.

We guarantee that your package will pass 100% through the Mexico US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.

 

We have freight forwarders in these countries, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.

Company Introduction

hebei yanxi chemical  co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and development production of reagent tens of thousands of species. our aim is quality strives for the survival. Seek development by credit reputation. Our products have big price advantage in Europe South America and so on .and Our company also has the advantage of high quality in Africa. in the past two years our products has reached more than 30 countries in the world, Europe. South America. North America, southeast Asia, Africa, etc. We welcome all over the world with the best quality and lowest price friend common cooperation and common development!

After Sales Service

 1) Best quality in your requirement

 2)Competitive price in china market

 3)Mature technical support

 4)Professional logistic support

 5 )Full experience of large numberscontainers loading in chinese sea port

 6 )Fast shipment by reputed shipping line

 7) Packing with pallet as buyer's special request

 8) Best service after shipment.

 9) Cargoes together with container after-sales service available

 10) Full experience in export

 11)Raw materials from chinese origin                                                                  

FAQ

 

What is the way you ship

Express: FedEx, UPS, EMS, DHL, USPS, TNT, DPD, Aramex etc

Our way of shipping the products is universal and secure.

The company name and other contents related to pharmacy are not written on the package slips.

The way of packing is regularly changed for a secure delivery.

The packages are small in order to avoid unwelcomed questions . If the order is big, then it will be divided into two or more packages

 

Can the packages be trackable

YES, we provide tracking number and you can track on internet.

 

Where do you ship to

Worldwide.

 

Do you offer domestic shipping/remail shipping

Yes we can ship to USA/UK/Canada/Australia/Germany etc warehouse first then to you.

 

Do you ensure your packing , what about customs, what happens if the package is retained

We concern a lot about our safety system, we pack the orders as secure as possible. If a package is seized at customs, reships of seized orders will be done provided you have a copy of the letter to show us. If you receive a seizure letter, please contact us immediately with a scanned copy of the seizure letter, and also a new address to have your order reshipped to.

 

Which payment options are available

Bitcoin

?

Bank wire

MoneyGram