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(2S)-beta-Alanyl-L-prolyl-2,4-diamino-N-(phenylmethyl)butanamide acetate SYN-AKE Dipeptide Diaminobutyroyl Benzylamide Diacetate;Syn-Ake
Snake venom peptide is a substance secreted by the snake glands of venomous snakes. It has pharmacological effects such as analgesia, hemostasis, inhibition of thrombosis and anti-tumor. Some snake venom preparations have been made and used in clinic. However, because snake venom peptide is the most complex composition of animal poisons, each snake venom contains active ingredients, roughly estimated to be at least 20, mainly including various toxins, enzymes and active peptides, most of the active components directly into the body may cause the body to produce serious side effects, such as cardiotoxicity, neurotoxicity, etc. These side effects are the main reasons that limit the application of snake venom preparations in clinical treatment.
Venom like peptides act as effective smoothing and wrinkle-removing active products by relaxing facial muscles in a manner consistent with the neuromuscular blocking compound Waglerin1 in TempleViper venom. Ophiotoxin-like peptides act on the postsynaptic membrane and are reversible antagonists of the muscular nicotine-acetylcholine Chemicalbook receptor (nmAChR). Serpentin-like peptides bind to epsilon subunits of nmAChR to block the binding of acetylcholine to the receptor, resulting in receptor closure, in which sodium ions cannot be taken in, depolarization cannot be prevented, nerve excitation transmission is blocked, and muscle relaxation is thus caused.
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