Pyrantel pamoate

Pyrantel pamoate
Pyrantel pamoate
Pyrantel pamoate
Pyrantel pamoate
Pyrantel pamoate

Pyrantel pamoate

Min.Order / FOB Price:Get Latest Price

1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : T/T,Other

Keywords

Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-[2-(-2-thienyl)ethenyl-, (E)-, with 4,4-methylenebis[3-hydroxy-2-naphthalenecarboxylic acid (1:1) 2-Naphthalenecarboxylic acid, 4,4-methylenebis[3-hydroxy-, compd. with (E)-1,4,5, 6-tetrahydro-1-methyl-2-[2-(2-thienyl)ethenyl]pyrimidine (1:1) 2-Naphthoic acid, 4,4-methylenebis[3-hydroxy-, compd. with (E)-1,4,5, 6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine (1:1)

Quick Details

  • Appearance:Light yellow powder
  • Application:Pharmaceutical intermediates
  • PackAge:Plastic bags, drums
  • ProductionCapacity:100000|Kilogram|Month
  • Storage:Sealed in dry,Room Temperature
  • Transportation:By sea,air or land

Superiority:

Yiwu Demei Electronic Commerce Firm is a modern high-tech chemical enterprise engaged in the research, development, production and sales of pharmaceutical raw materials and organic intermediates. It is committed to making its own contribution to the export of Chinese pharmaceutical chemicals to all over the world. In recent years, our products have also been exported to the UK, Germany, Australia, the Netherlands, Poland, Russia, Kazakhstan, the Philippines, Malaysia, Singapore and many other regions. we do business with customers based on the principle of honesty and trustworthiness. 

 

MATERIALS & TRANSPORTATION
Materials and transportation include: sea transportation, air transportation, railway transportation, truck transportation, large truck transportation, etc.

The weight ranges from grams to tons, which can meet almost all the inner needs of customers. In terms of product quality and product price, we have also made statistics on the current Chinese market. We strive to provide customers with the most advantageous price under the premise of the same quality.

FAQ

1.How can I get the samples?
  For some products,we can provide you with free off the shelf samples.You just need to pay for delivery.
2.Can you provide relevant documents?
  Of course.We can provide commercial invoice,packing list,bill of lading etc.If your market has any special requirements,just let me know.
3.How long will it take to deliver payment?
  The goods will be delivered within 1-3 days.And you will get the product within 7-10 days.It's safe and fast door to door delivery.
4.What's your payment terms?
  We support the ,Money Gram,Bitcoin,T/T,Alibaba,Alipay etc.

Details:

Specification

Common Name Pyrantel pamoate
CAS Number 22204-24-6
Molecular Weight 594.677
Molecular Formula C34H30N2O6S
Density N/A
Boiling Point 642.7ºC at 760 mmHg
Melting Point 266-267ºC
Flash Point 356.5ºC
Exact Mass 594.182434
PSA 158.90000
LogP 6.26020
Vapour Pressure 2.13E-17mmHg at 25°C
Index of Refraction N/A
Storage condition 0-6°C
EINECS 244-837-1

Application

Biological Activity
Pyrantel pamoate (Pyrantel Embonate) is a broad-spectrum anthelmintic used to treat some parasitic infections.
In vitro studies

Pyrantel induces Ascaris suum muscle contraction, with a EC50 of 7.24.

Pyrantel produces spastic paralysis of the nematode by selectively gating acetylcholine receptor ion-channels on nerve and muscle.

Pyrantel (72h) inhibits the survival of Ancylostomaceylanicum, Necator Chemicalbookamericanus and Trichurismu rison the third-stage larvae (IC50s=90.9, 2.0, and 95.5µg/mL, respectively) and adult worms (IC50s=>100, 7.6, and 34.1µg/mL, respectively).
In vivo studies

Pyrantel (10mg/kg; as a single p.o.) reduces the worms in A.ceylanicum-infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%.


Chemical properties Yellow to brown crystalline powder

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