- Min.Order :1 Kilogram
- Purity: 99%
- Payment Terms : L/C,T/T
Keywords
Entrectinib Entrectinib(NMS-E628) N-(5-(3,5-difluorobenzyl)-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)benzamide
Quick Details
- Appearance:white powder
- Application:Entrectinib is a potent, orally active inhibitor of Trk, ROS1, and ALK
- PackAge:fiber can
- ProductionCapacity:200|Kilogram|Year
- Storage:Store at 2-8°C
- Transportation:air transport
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Details:
English name: Entrectinib
English synonyms: N-[5-[(3, 5-difluorophenyl)methyl] -1h-indazol-3-yl]-4-(4-methyl-1-piperazinyl)-2-[(tetrChemicalbookahydro-2H-pyran-4) -yl)amino]benzamide; Entrectinib; Entrectinib(NMS-E628); N - (5 - (3, 5 - difluorobenzyl) 1 h - indazol - 3 - yl) - 4 - (4 - methylpiperazin - 1 - yl) - 2 - (tetrahydro - 2 h - pyran 4 - ylamino) benzamide; RXDX-101; Entrectinib,NMS-E628,RXDX-101; entrecitinib; Entrectinib(RXDX-101)
CAS number: 1108743-60-7
Molecular formula :C31H34F2N6O2
Molecular weight ：560.64
Entrectinib is a potent, orally active inhibitor of Trk, ROS1, and ALK; The IC50 values for inhibiting TrkA, TrkB, TrkC, ROS1 and ALK were 1, 3, 5, 12 and 7 nM, respectively.
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