Ginkgo Biloba Extract

Details:

Ginkgo biloba  Extract 
Part Used:leaf

Ginkgo Biloba Extract is the dried leaf extract of Ginkgo biloba, a light yellowish brown movable powder.

On October 27, 2017, the World Health Organization's International Agency for Research on Cancer published a preliminary reference list of carcinogens, Ginkgo Biloba Extract in the 2B list of carcinogens.

Ginkgo Biloba Extract is a kind of product with ginkgo biloba as raw material, using appropriate solvent, and enriching the active components extracted. Various preparations made with GBE as raw materials are widely used in medicine, health care products, food additives, functional drinks, cosmetics and other fields. Ginkgo Biloba Extract is a light yellowish brown movable powder with aroma and bitter taste.

1.Antioxidant Activity
Ginkgolides possess strong antioxidant properties. They can scavenge free radicals in the body, such as reactive oxygen species (ROS) and hydroxyl radicals. By reducing oxidative stress, they help protect cells from damage. This antioxidant effect is beneficial for maintaining the normal structure and function of cell membranes, proteins, and nucleic acids. For example, they can prevent lipid peroxidation in cell membranes, which is often associated with various diseases and aging processes.
 
2.Anti - platelet Aggregation
One of the significant functions of ginkgolides is their ability to inhibit platelet aggregation. They act on platelet activation pathways and interfere with the binding of platelet - activating factors (PAF). By blocking the action of PAF, ginkgolides can reduce the risk of blood clot formation. This property has important implications for cardiovascular health as it helps prevent thrombotic disorders like stroke and myocardial infarction.
 
3.Neuroprotective Effects
Ginkgolides have demonstrated neuroprotective effects. They can improve blood circulation in the brain by dilating blood vessels. This enhanced blood flow ensures an adequate supply of oxygen and nutrients to brain cells. Additionally, they can protect neurons from damage caused by ischemia - reperfusion injury, excitotoxicity, and oxidative stress. For instance, in some experimental models of cerebral ischemia, ginkgolides have been shown to reduce the size of the infarct area and improve neurological function recovery.
 
4.Anti - inflammatory Effects
These compounds also exhibit anti - inflammatory activities. They can regulate the expression of inflammatory cytokines and chemokines, and inhibit the activation of inflammatory cells such as macrophages. By reducing the inflammatory response, ginkgolides are beneficial in various inflammatory - related diseases, including those affecting the respiratory system and the nervous system. For example, they may alleviate airway inflammation in some respiratory disorders

1. Pharmaceutical Industry
Cardiovascular Drugs: Due to their anti - platelet aggregation and vasodilatory effects, ginkgolides are used in the development of drugs for the prevention and treatment of cardiovascular diseases. They can be formulated into medications to reduce the risk of thrombosis and improve blood circulation in patients with coronary heart disease, angina pectoris, or other related conditions.
Neurological Medications: In the field of neurology, ginkgolides are applied in drugs designed to treat various neurological disorders. For example, they are used in the treatment of cerebrovascular insufficiency, dementia, and some types of peripheral neuropathy. Their ability to improve cerebral blood flow and protect neurons makes them valuable in these therapeutic applications.
Anti - inflammatory Drugs: Ginkgolides can be incorporated into anti - inflammatory drugs. They are useful in treating conditions such as chronic bronchitis, asthma, and other inflammatory diseases of the respiratory tract. Their anti - inflammatory properties can help reduce symptoms and improve the quality of life of patients.
 
2. Cosmetic Industry
Anti - aging Products: The antioxidant properties of ginkgolides make them ideal ingredients for anti - aging cosmetics. They can be added to creams, serums, and lotions to protect the skin from oxidative damage caused by environmental factors such as ultraviolet radiation and pollution. By reducing free radical damage, ginkgolides can help maintain the elasticity and firmness of the skin, reducing the appearance of wrinkles and fine lines.
Skin - protecting Products: Ginkgolides also have potential in skin - protecting products. Their anti - inflammatory effects can soothe irritated skin and reduce redness. They can be used in products for sensitive skin or those designed to protect the skin from external irritants.
3. Food Supplements
Ginkgolides can be used in food supplements. They provide antioxidant and potential health - promoting benefits. Supplements containing ginkgolides may be beneficial for people concerned about cardiovascular health, brain function, or overall well - being. They can be formulated as tablets, capsules, or added to functional foods such as energy bars or health drinks.