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Appearance: White powder Molecular Formula：C13H 17N 5O 8S 2 Molecular weight：435.43 Purity：≥98% (HPLC) D[25℃] ： -26 ～ -32 Usag…
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Appearance: White powder Molecular Formula：C13H 17N 5O 8S 2 Molecular weight：435.43 Purity：≥98% (HPLC) D[25℃] ： -26 ～ -32 Usage：antibody Related information of Aztreonam Aztreonam is a monobactam (monocyclic beta-lactam nucleus) antibiotic. It has side chains for activity enhencing and stability. It inhibits cell wall biosynthesis by binding to penicillin-binding protein of aerobic gram-negative bacilli. It has very active and broad spectrum activity against aerobic-gram negative bacteria, including Pseudomonas aeruginosa, Hemophilus influenzae, Enterobacteriaceae, and Neisseria gonorrhea; This spectrum is similar to the 3rd generation cephalosporins or aminoglycosides. As it has limited activity to only aerobic-gram negative bacteria, it is used in combination with gram-positive bacteria anaerobes sometimes. It is frequently used in patients unable to tolerate beta-lactams.It is resistant to beta-lactamases and is useful against gram-negative pathogens. The chemical designation is 2-[(Z-(2)-Aminothiazol-4-yl)-2-[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin -3-yl-carbamoyl]methyleneaminooxy]-2- methyl-1-propanoic acid. It is a white crystalline powder, odorless. Commercial aztreonam is the mixture with arginine (apprx 4:3).
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