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Diltiazem hydrochloride is a common antihypertensive drug. It is a Class B drug in the National Medical Insurance Catalogue and is a prescription drug. Diltiazem is a benzothiazepine calcium channel blocker, a third-generation antianginal drug and a fourth-generation antiarrhythmic drug. It is mainly used for coronary heart disease, angina pectoris, and mild and moderate hypertension. It is particularly suitable for hypertensive patients with coronary heart disease and angina pectoris.

The effect of diltiazem is related to the inhibition of calcium ion influx during myocardial and vascular smooth muscle depolarization; the product can effectively dilate the epicardial and subendocardial coronary arteries, relieve spontaneous angina pectoris or angina pectoris caused by coronary artery spasm induced by ergonovine; by slowing down the heart rate and lowering blood pressure, it reduces myocardial oxygen demand, increases exercise tolerance and relieves exertional angina pectoris. The product can relax vascular smooth muscle, reduce peripheral vascular resistance, and lower blood pressure. The extent of its blood pressure reduction is related to the degree of hypertension. For people with normal blood pressure, it only slightly reduces blood pressure. This product has a negative inotropic effect and can slow down the conduction of the sinoatrial node and atrioventricular node.

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