Trimethylsulfoxonium Bromide

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Description of Trimethylsulfoxonium Bromide from Watson Biotechnology Co., Ltd

Specifications(COA) of Trimethylsulfoxonium Bromide CAS 25596-24-1 TMSB Chemical Reagent

Trimethylsulfoxonium bromide (TMSB) is a chemical reagent with several notable applications, primarily in organic synthesis. Some of its key applications include:

1. Epoxidation Reactions: TMSB is often used as a precursor for generating dimethyloxosulfonium methylide, a reactive intermediate in the formation of epoxides from carbonyl compounds (such as aldehydes and ketones). This process is known as Corey-Chaykovsky epoxidation.

2. Ylide Chemistry: TMSB is a source of sulfoxonium ylides, which are important intermediates in organic synthesis. These ylides are nucleophilic species that can react with electrophiles to form a variety of cyclic and heterocyclic compounds.

3. Cyclopropanation: Through the generation of sulfoxonium ylides, TMSB is also used to convert carbonyl compounds into cyclopropanes via a nucleophilic attack, offering a versatile method to create three-membered ring systems.

4. Stereoselective Synthesis: TMSB is utilized in the synthesis of stereoselective products due to the controlled generation of ylides and their highly selective reactions with electrophilic centers.

5. Synthesis of Carbenoids: In combination with other reagents, TMSB helps in generating metal carbenoids, which are useful for various carbon–carbon bond-forming reactions, including insertions and cycloadditions.

Overall, TMSB serves as a versatile reagent in a wide range of organic transformations, especially those involving the formation of small ring systems and heterocyclic compounds.

Founded in 2006 and headquartered in Wuhan, Hubei, China, Watson Biotechnology Co., Ltd is a leading manufacturing powerhouse specializing in the production of Active Pharmaceutical Ingredients (APIs) and Intermediates, Food and Feed Additives, Agricultural and Aquaculture chemicals, and Fine Chemicals. As a dedicated factory, our operations are driven by a commitment to excellence and innovation, ensuring that our products meet the highest standards of quality and compliance.

With a robust team of over 100 skilled professionals, Watson Biotechnology has established itself as a trusted name in the industry. Our products are meticulously crafted to align with international standards such as USP (United States Pharmacopeia), EP (European Pharmacopoeia), and BP (British Pharmacopoeia), guaranteeing reliability and efficacy.

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