Benzoic acid, p-(butylamino)-, 2-(dimethylamino)ethyl ester, monohydrochloride(8CI) 2-(Dimethylamino)ethyl p-(butylamino)benzoate hydrochloride Amethocainehydrochloride
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Common name: Tetracaine hydrochloride
CAS No.: 136-47-0
EINECS No.: 205-248-5
Appearance:Solid
Molecular formula: C15H25ClN2O2
Brand Name: Colorcom
Shelf Life: 2 Years
Place of Origin: China
Product Specification:
Molecular Weight |
300.82 |
Boiling point |
/ |
Melting point |
149°C |
Density |
1.1279 (rough estimate) |
Purity |
≥99.0% |
Acidity coefficient (pKa) |
8.39(at 25℃) |
Soluble |
Alcohol: Soluble in 40 parts solvent |
Water solubility |
Soluble in water at 50mg/ml |
Color |
White |
Product Description:
Tetracaine hydrochloride is a highly effective local anesthetic that can block nerve function reversibly. It is used in infiltration anesthesia, nerve block anesthesia, epidural anesthesia, etc. Compared with procaine, tetracaine has remarkable local anesthetic effect and has been widely used in clinic. It is found that the synthesis of p-butylaminobenzoic acid is the key step in the synthesis of tetracaine hydrochloride, which has the disadvantages of unstable raw materials or low yield. Scientists have improved and improved this, in 1981 proposed to synthesize p-butylaminobenzoic acid by alkylation of p-aminobenzoic acid with 1-bromobutane, but because it can not avoid the generation of double butylated by-products, and the nature of the raw material itself is unstable, making this route is not suitable for industrial production.
Application:
Used as a local anesthetic
Package: 25kg/Barrel, 100kg
Storage: 2-8°C
Executive Standards: International Standard.
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