4,5-Dihydroxyanthraquinone-2-c

Details:

Company Profile:

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards.

Colorcom prides itself on superior customer and technical focus, while focusing on support, developing and manufacturing superior colorants and specialty chemicals. All of our industrial chemical manufacturing is executed to enhance the performance, appeal and processing of a broad range of products used in various industries and consumer - based applications.

Product Description:

— Rhein is an organic compound that is a coffee colored needle crystal, which sublimates into a yellow needle crystal. Insoluble in water, soluble in pyridine and sodium bicarbonate aqueous solutions, slightly soluble in ethanol, benzene, chloroform, ether, and petroleum ether. 

Product Name: Rhein

Other Names: 4,5-Dihydroxyanthraquinone-2-c

Category: Pharmaceutical Intermediates

CAS No.:  478-43-3

EINECS: 207-521-4

Appearance:Coffee colored needle crystal

Molecular Formula: C15H8O6

Brand Name: Colorcom

Shelf Life: 2 Years

Place of Origin:China

Package: 25 kgs/bag or as you request.

Storage: Store at a ventilated, dry place.

Executive Standard: International Standard.

 

Application:

Used as a raw material for the synthetic arthritis medicine diacetate abroad; In addition, rhein is the best raw material for preparing health products, which can reduce fat, lose weight, promote bowel movements and detoxification, clean the internal environment, prevent gastric cancer, and delay aging.

 

Product Features:

Multifaceted Pharmacological Effects

• Anti-inflammatory: Potently inhibits NF-κB and MAPK pathways, reducing TNF-α and IL-6 (IC50 ~5–10 μM)

• Antifibrotic: Blocks TGF-β1/Smad signaling for liver/lung fibrosis treatment

• Renoprotective: Activates Nrf2/HO-1 to alleviate diabetic nephropathy

 Broad-Spectrum Anticancer Mechanisms

• Metabolic Disruption: Targets HK2 and PKM2 to suppress glycolysis

• Epigenetic Modulation: Downregulates DNMT1 to reactivate tumor suppressors

• Ferroptosis Induction: Enhances cancer cell sensitivity via GPX4/ACSL4 regulation

Product Specification:

Item	RESULT
Formula	C15H8O6
Molecular Weight	284.2204
Melting Point	321-322℃
Boiling Point	597.85℃
Flash Point	329.40℃
Package	25KG
Purity	98%; 99%

Guidelines for use and Cautions:

• Enteric coating required for pH-sensitive formulations

• Avoid cationic drug combinations (risk of insoluble complexes)

• Monitor plasma levels in UGT1A1*28 polymorphism patients

Our Services:

Our advantage:

The competitive advantages of Colorcom international as your business partner or supplier:

1.Established manufacturer.
2.Current ISO certified; REACH registered.
3.Track record of quality, Lot to lot consistency.
4.Zero defect, Return policy.
5.Sufficient inventory.
6.Wide product portfolio, A great choice of shades.
7.Joint product development.
8.Total innovative solutions for every industry of the specific requirements.
9.Open dialogue and communication channels.
10.Long term commitment to meet or exceed the expectations of customers.
11.Competitive pricing, Optimistic margin.
12.Providing efficient service which is second to none.
13.Constantly changing industry requirements for innovative, fully customized products and solutions.
14.Consistent color performance, adaptability, flexibility and customization.
15.26 years of chemical industry knowledge and experience.
16.Colorcom makes every effort to better serve the global customers,We create and bring the best values to you.

Certifications:

Why Choose us:

Contact us:

Colorcom Group produces high performance pigments widely use in printing inks, paints, coatings,plastic, textile printings, leathers, stationery, construction, cosmetics,etc.Our brand are TPColor &TopColor,which are now a renown brand for international market.Our TPColor pigments have the advantages of high color strength, high gloss, superior dispersion, excellent fastness to light and weather,outstanding resistance to all solvents, high quality consistency,long shelf-life, chemically and physically stable, etc.

Colorcom Ltd was established in May, 2013 to be in charge of the import and export business for our group, with the registered capital of CNY: 10,000,000.00. The company is headquartered in Hangzhou city, Zhejiang province, which is the very famous scenery city in China. Welcome to visit our company. We will have a very pleasant time together in the place of interest ......