Cocarboxylase Thiamine Pyrophosphate Thiamine diphosphate chloride
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Product name |
Thiamine Pyrophosphate; Thiamine diphosphate chloride; Cocarboxylasee; TPP |
CAS No. |
154-87-0 |
Molecular Formula |
C12H19N4O7P2S.Cl |
Molecular Weight |
460.772 |
Quality Standard |
98% up by HPLC |
Appearance |
White to off-white powder |
ANALYSIS |
SPECIFICATION |
RESULTS |
Appearance |
White to off-white powder |
White powder |
Purity by HPLC |
≥ 98.00% |
99.12% |
Solubility |
Solution in water |
Clear solution |
pH in water ( 1mg/ml) |
≤0.25% |
0.17% |
Loss on dry |
≤5% |
1.3% |
Ash |
5.6% |
|
H-NMR |
Complied with the structure |
|
31P-NMR |
99.57% |
|
|
Thiamine Pyrophosphate (TPP), also known as Thiamine diphosphate chloride/ Cocarboxylase, is the active form of Vitamin B1 (thiamine) and plays a crucial role as a coenzyme in the body. TPP is essential in carbohydrate metabolism, particularly in the decarboxylation of alpha-keto acids. It serves as a necessary cofactor for transketolase in the cytoplasm and for pyruvate, alpha-ketoglutarate, and branched-chain alpha-keto acid dehydrogenases in the mitochondria, which are vital for maintaining nervous system health and converting food into energy.
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