Thiamine diphosphate chloride

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Purity: 99% up by HPLC

Keywords

Cocarboxylase Thiamine Pyrophosphate Thiamine diphosphate chloride

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Product name	Thiamine Pyrophosphate; Thiamine diphosphate chloride; Cocarboxylasee; TPP
CAS No.	154-87-0
Molecular Formula	C12H19N4O7P2S^.Cl
Molecular Weight	460.772
Quality Standard	98% up by HPLC
Appearance	White to off-white powder

ANALYSIS	SPECIFICATION	RESULTS
Appearance	White to off-white powder	White powder
Purity by HPLC	≥ 98.00%	99.12%
Solubility	Solution in water	Clear solution
pH in water ( 1mg/ml)	≤0.25%	0.17%
Loss on dry	≤5%	1.3%
Ash	5.6%
H-NMR	Complied with the structure
³¹P-NMR	99.57%

Thiamine Pyrophosphate (TPP), also known as Thiamine diphosphate chloride/ Cocarboxylase, is the active form of Vitamin B1 (thiamine) and plays a crucial role as a coenzyme in the body. TPP is essential in carbohydrate metabolism, particularly in the decarboxylation of alpha-keto acids. It serves as a necessary cofactor for transketolase in the cytoplasm and for pyruvate, alpha-ketoglutarate, and branched-chain alpha-keto acid dehydrogenases in the mitochondria, which are vital for maintaining nervous system health and converting food into energy.

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