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4-[3-(4-cyano-2-fluoro-3-trifluoromethyl-phenyl)-5,5-dimethyl-4-oxo-2-thioxo-imidazolidin-1-yl]-2-fluoro-N-methyl-benzamide KX-826 Pyrilutamide
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Factory Supply Kx-826 /Pyrilutamide CAS. 1272719-0-2 of Hair Regrowth Kx 826 99% Minoxidil
Product Name | KX-826 |
CAS No. | 1272719-0-2 |
Color | white |
Appearance | Powder |
Storage | KX826 should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
Shelf Life | 2 years |
Purity | 98% + |
What is KY 826?
KX-826 is a new investigational androgen receptor (AR) antagonist for the treatment of male pattern hair loss (androgenetic alopecia). A total of 120 subjects will be randomized to one of four cohorts: 2.5 mg BID, 5 mg QD, 5mg BID of KX-826 or placebo (BID or QD) for 24 weeks. The primary endpoint of the study is to assess the changes from baseline in non-vellus TAHC (Target Area Hair Counts)at Week 24 in comparison to placebo.
Pyrilutamide, also known as KX-826, is a non-steroidal anti-androgen that works by blocking androgens such as testos one and DHT from binding with the androgen receptor. It was developed by a biotech company called Kintor Pharmaceuticals.
Pyrilutamide (developmental code name KX-826) is a nonsteroidal antiandrogen (NSAA) - specifically, a selective high-affinity antagonist of the androgen receptor (AR). It has a high affinity of IC50 of 0.28nM, with the androgen receptor.
Pyrilutamide inhibits the signaling pathway mediated by androgens and their receptors locally, and finasteride systemically inhibits androgens by competing with androgens in the target organizer for binding to androgen receptors. Different from DHT synthesis to stimulate hair growth, this mechanism avoids the reduction of systemic androgen levels and the resulting clinical side effects while blocking the signal transmission to stimulate hair growth.
FAQ
Q1: Can i get some samples
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or Paypal or Escrow(Alibaba).
Q3: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What's your MOQ
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery leadtime
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6:Is there a discount
A:Different quantity has different discount.
Q7: How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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